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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL15456
Molecular formula	C23H27Cl2N3OS
IUPAC name	6-[4-[4-[(3,4-dichlorophenyl)methyl]piperazin-1-yl]butyl]-3-methyl-1,3-benzothiazol-2-one
Molecular weight	464.449
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.4
Synonyms	3-Methyl-6-[4-[4-(3,4-dichlorobenzyl)piperazino]butyl]benzothiazoline-2-one BDBM50111628 6-{4-[4-(3,4-Dichloro-benzyl)-piperazin-1-yl]-butyl}-3-methyl-3H-benzothiazol-2-one
Inchi Key	HXCDEZDRGXIHKK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H27Cl2N3OS/c1-26-21-8-6-17(15-22(21)30-23(26)29)4-2-3-9-27-10-12-28(13-11-27)16-18-5-7-19(24)20(25)14-18/h5-8,14-15H,2-4,9-13,16H2,1H3
PubChem CID	10027435
ChEMBL	CHEMBL15456
IUPHAR	N/A
BindingDB	50111628
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
126050	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
126052	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
126048	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
126049	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
126051	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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