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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL326821
Molecular formula	C20H22ClN3O
IUPAC name	1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl)piperazin-1-yl]ethanone
Molecular weight	355.866
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	2.6
Synonyms	8-CHLORO-11-(1-ACETYL-4-PIPERAZINYL)-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-b]PYRIDINE Sch-40338 1-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}piperazin-1-yl)ethan-1-one GTPL1854 AIESXMXVDNOKQF-UHFFFAOYSA-N SCHEMBL8877591 1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-ethanone SCH 40338 BDBM50073173 117796-62-0 D0Q8YN [ Show all ]
Inchi Key	AIESXMXVDNOKQF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22ClN3O/c1-14(25)23-9-11-24(12-10-23)20-18-7-6-17(21)13-16(18)5-4-15-3-2-8-22-19(15)20/h2-3,6-8,13,20H,4-5,9-12H2,1H3
PubChem CID	9950564
ChEMBL	CHEMBL326821
IUPHAR	1854
BindingDB	50073173
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6146	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
553270	Platelet-activating factor receptor	P25105	PTAFR	Homo sapiens (Human)	342

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