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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL366388
Molecular formula	C24H29FN2O
IUPAC name	1-(4-fluorophenyl)-4-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)piperazin-1-yl]butan-1-one
Molecular weight	380.507
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.1
Synonyms	BDBM50056946 1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-naphthalen-1-yl)-piperazin-1-yl]-butan-1-one
Inchi Key	JGHINESLHSSDOZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29FN2O/c25-21-12-10-20(11-13-21)24(28)9-4-14-26-15-17-27(18-16-26)23-8-3-6-19-5-1-2-7-22(19)23/h1-2,5,7,10-13,23H,3-4,6,8-9,14-18H2
PubChem CID	9864676
ChEMBL	CHEMBL366388
IUPHAR	N/A
BindingDB	50056946
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
150284	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
150288	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
150286	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
150285	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444
150287	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486

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