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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL333455
Molecular formula	C18H22FN3S
IUPAC name	6-(4-ethylpiperazin-1-yl)-8-fluoro-5,6-dihydropyrrolo[2,1-b][1,3]benzothiazepine
Molecular weight	331.453
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.9
Synonyms	BDBM50108592 SCHEMBL7488822 (+/-)9-(4-Ethyl-piperazin-1-yl)-7-fluoro-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene
Inchi Key	HXNZZHNYAXGYCA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H22FN3S/c1-2-20-8-10-21(11-9-20)16-13-22-7-3-4-18(22)23-17-6-5-14(19)12-15(16)17/h3-7,12,16H,2,8-11,13H2,1H3
PubChem CID	9949441
ChEMBL	CHEMBL333455
IUPHAR	N/A
BindingDB	50108592
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
126453	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
126452	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
126454	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
126455	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
126456	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
126457	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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