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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL344942
Molecular formula	C21H21FN2O
IUPAC name	1-[4-(13-fluoro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]ethanone
Molecular weight	336.41
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.9
Synonyms	1-[4-(8-Fluoro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-ethanone BDBM50007462 SCHEMBL8879488 5,6-Dihydro-11-(1-acetyl-4-piperidinylidene)-8-fluoro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine
Inchi Key	HVNPGDRVEITEIV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H21FN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
PubChem CID	14885628
ChEMBL	CHEMBL344942
IUPHAR	N/A
BindingDB	50007462
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
125126	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
125125	Platelet-activating factor receptor	P25105	PTAFR	Homo sapiens (Human)	342

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