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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL536747
Molecular formula	C35H45F2N3
IUPAC name	1-[3-(2-fluoro-6-phenylphenyl)propyl]-4-[2-(4-fluorophenyl)-2-(1-propan-2-ylpiperidin-4-yl)ethyl]piperazine
Molecular weight	545.763
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	7.5
Synonyms	BDBM50203996 (+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-(1-isopropylpiperidin-4-yl)ethyl]piperazine trihydrochloride CHEMBL1188561
Inchi Key	DHUKBDYVZDFTNL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C35H45F2N3/c1-27(2)40-20-17-30(18-21-40)34(29-13-15-31(36)16-14-29)26-39-24-22-38(23-25-39)19-7-11-33-32(10-6-12-35(33)37)28-8-4-3-5-9-28/h3-6,8-10,12-16,27,30,34H,7,11,17-26H2,1-2H3
PubChem CID	44423378
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50203996
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
60387	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
60386	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
60385	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
459774	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
60388	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398

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