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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL15499
Molecular formula	C16H23N3OS
IUPAC name	6-[2-[(3S,5R)-3,5-dimethylpiperazin-1-yl]ethyl]-3-methyl-1,3-benzothiazol-2-one
Molecular weight	305.44
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.5
Synonyms	6-[2-((3R,5S)-3,5-Dimethyl-piperazin-1-yl)-ethyl]-3-methyl-3H-benzothiazol-2-one 3-Methyl-6-[2-[(3S)-3alpha,5alpha-dimethylpiperazino]ethyl]benzothiazoline-2-one BDBM50111635
Inchi Key	JJZCOPQZNMJSKH-TXEJJXNPSA-N
Inchi ID	InChI=1S/C16H23N3OS/c1-11-9-19(10-12(2)17-11)7-6-13-4-5-14-15(8-13)21-16(20)18(14)3/h4-5,8,11-12,17H,6-7,9-10H2,1-3H3/t11-,12+
PubChem CID	44270248
ChEMBL	CHEMBL15499
IUPHAR	N/A
BindingDB	50111635
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
152775	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
152776	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
152774	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
152772	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
152773	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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