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| Name | Vasopressin V1b receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Avpr1b |
| Synonym | Vasopressin V3 receptor vasopressin V1b receptor V3/V1b pituitary vasopressin receptor V3 V1bR [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 425 |
| Amino acid sequence | MNSEPSWTATPSPGGTLPVPNATTPWLGRDEELAKVEIGILATVLVLATGGNLAVLLTLGRHGHKRSRMHLFVLHLALTDLGVALFQVLPQLLWDITYRFQGSDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLRQPSQSTYPLIAAPWLLAAILSLPQVFIFSLREVIQGSGVLDCWADFYFSWGPRAYITWTTMAIFVLPVAVLSACYGLICHEIYKNLKVKTQAGREERRGWRTWDKSSSSAVATAATRGLPSRVSSISTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDENAPNEDSTNVAFTISMLLGNLSSCCNPWIYMGFNSRLLPRSLSHHACCTGSKPQVHRQLSTSSLTSRRTTLLTHACGSPTLRLSLNLSLRAKPRPAGSLKDLEQVDGEATMETSIF |
| UniProt | P48974 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2659 |
| IUPHAR | 367 |
| DrugBank | N/A |
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| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 17410 |  CHEMBL583082 | C29H37N3O6S3 | 619.81 | 10 / 1 | 4.0 | No |
| 29839 |  CHEMBL572754 | C30H43N3O7S2 | 621.808 | 10 / 1 | 3.4 | No |
| 34744 |  CHEMBL575359 | C27H30ClN3O3S2 | 544.125 | 6 / 1 | 4.5 | No |
| 36001 |  CHEMBL576147 | C27H31ClN4O3S2 | 559.14 | 6 / 2 | 4.4 | No |
| 37059 |  d[Cha4,Orn8]VP | C49H69N11O11S2 | 1052.28 | 14 / 11 | 0.5 | No |
| 53747 |  d[Leu4]AVP | C47H67N13O11S2 | 1054.25 | 14 / 12 | -1.5 | No |
| 65995 |  d[Cha4,Dab8]VP | C48H67N11O11S2 | 1038.25 | 14 / 11 | 0.1 | No |
| 76403 |  d[Arg4,Orn8]VP | C46H66N14O11S2 | 1055.24 | 15 / 13 | -3.4 | No |
| 88541 |  d[Leu4,Orn8]VP | C46H65N11O11S2 | 1012.21 | 14 / 11 | -0.9 | No |
| 108930 |  CHEMBL575796 | C29H43N3O6S2 | 593.798 | 9 / 1 | 4.5 | No |
| 110957 |  d[Orn4]AVP | C46H66N14O11S2 | 1055.24 | 15 / 13 | -3.4 | No |
| 135242 |  Conivaptan | C32H26N4O2 | 498.586 | 3 / 2 | 5.7 | No |
| 148611 |  CHEMBL1204403 | C31H46ClN3O6S2 | 656.294 | 9 / 2 | N/A | No |
| 159564 |  CHEMBL1204126 | C31H46BrN3O6S2 | 700.748 | 9 / 2 | N/A | No |
| 159805 |  d[Arg4,Dab8]VP | C45H64N14O11S2 | 1041.21 | 15 / 13 | -3.8 | No |
| 163811 |  CHEMBL575797 | C28H39N3O6S2 | 577.755 | 9 / 1 | 3.5 | No |
| 165540 |  ARGIPRESSIN | C46H65N15O12S2 | 1084.24 | 16 / 14 | -4.8 | No |
| 166854 |  d[D-3-Pal2]AVP | C45H63N15O11S2 | 1054.21 | 15 / 12 | -4.7 | No |
| 166899 |  d[Val4]AVP | C46H65N13O11S2 | 1040.23 | 14 / 12 | -1.9 | No |
| 173437 |  CHEMBL575773 | C29H34ClN3O3S2 | 572.179 | 6 / 1 | 5.2 | No |
| 177197 |  Opc 21268 | C26H31N3O4 | 449.551 | 4 / 1 | 2.6 | Yes |
| 181347 |  d[Arg4,Lys8]VP | C47H68N14O11S2 | 1069.27 | 15 / 13 | -3.1 | No |
| 210509 |  CHEMBL1684574 | C27H33ClN4O3 | 497.036 | 5 / 1 | 4.5 | Yes |
| 217438 |  d[Orn4,Lys8]VP | C46H66N12O11S2 | 1027.23 | 15 / 12 | -2.5 | No |
| 221116 |  CHEMBL583081 | C29H37N3O6S3 | 619.81 | 10 / 1 | 4.0 | No |
| 222051 |  DESMOPRESSIN | C46H64N14O12S2 | 1069.22 | 15 / 13 | -4.0 | No |
| 222064 |  DESMOPRESSIN | C46H64N14O12S2 | 1069.22 | 15 / 13 | -4.0 | No |
| 222875 |  CHEMBL572921 | C26H30ClN3O4S3 | 580.173 | 8 / 1 | 4.3 | No |
| 225255 |  Nelivaptan | C30H32ClN3O8S | 630.109 | 9 / 1 | 3.4 | No |
| 226639 |  d[Orn4,Orn8]VP | C45H64N12O11S2 | 1013.2 | 15 / 12 | -2.8 | No |
| 227570 |  CHEMBL583083 | C31H39N3O6S2 | 613.788 | 9 / 1 | 4.3 | No |
| 227671 |  CHEMBL567176 | C28H34ClN3O2S2 | 544.169 | 6 / 1 | 5.8 | No |
| 229689 |  CHEMBL1684573 | C28H36N4O4 | 492.62 | 6 / 1 | 3.9 | Yes |
| 235946 |  d[Arg4]AVP | C47H68N16O11S2 | 1097.28 | 15 / 14 | -4.1 | No |
| 242833 |  CHEMBL575972 | C28H34ClN3O4S3 | 608.227 | 8 / 1 | 5.0 | No |
| 278071 |  d[Leu4,Lys8]VP | C47H67N11O11S2 | 1026.24 | 14 / 11 | -0.6 | No |
| 284546 |  CHEMBL574450 | C28H33ClN4O3S2 | 573.167 | 6 / 1 | 4.6 | No |
| 287930 |  Manning compound | C52H74N14O12S2 | 1151.37 | 15 / 12 | -2.1 | No |
| 291216 |  CHEMBL583084 | C32H41N3O7S2 | 643.814 | 10 / 1 | 4.3 | No |
| 298012 |  d[Cha4,Lys8]VP | C50H71N11O11S2 | 1066.3 | 14 / 11 | 0.8 | No |
| 305072 |  CHEMBL572760 | C31H38FN3O6S2 | 631.778 | 10 / 1 | 4.4 | No |
| 326250 |  CHEMBL572983 | C32H41N3O7S2 | 643.814 | 10 / 1 | 4.3 | No |
| 334891 |  SSR126768A | C33H31Cl2N3O4 | 604.528 | 5 / 0 | 6.0 | No |
| 345214 |  CHEMBL35226 | C21H29N3O | 339.483 | 4 / 1 | 4.5 | Yes |
| 352898 |  CHEMBL1223814 | C27H32N4O4 | 476.577 | 6 / 1 | 2.6 | Yes |
| 356306 |  d[Leu4,Dab8]VP | C45H63N11O11S2 | 998.185 | 14 / 11 | -1.3 | No |
| 367673 |  CHEMBL2092887 | C11H19ClN2O4S3 | 374.913 | 7 / 3 | N/A | N/A |
| 380572 |  Mozavaptan | C27H29N3O2 | 427.548 | 3 / 1 | 4.5 | Yes |
| 385527 |  CHEMBL577816 | C27H30ClN3O4S2 | 560.124 | 7 / 1 | 4.9 | No |
| 386764 |  d[Cha4,Dap8]VP | C47H65N11O11S2 | 1024.22 | 14 / 11 | -0.2 | No |
| 387405 |  CHEMBL572835 | C32H41N3O6S2 | 627.815 | 9 / 1 | 4.7 | No |
| 396502 |  CHEMBL265640 | C43H66N12O12S2 | 1007.19 | 15 / 12 | -2.6 | No |
| 397901 |  CHEMBL575987 | C27H39N3O6S2 | 565.744 | 9 / 1 | 3.7 | No |
| 398262 |  CHEMBL572709 | C31H45N3O6S2 | 619.836 | 9 / 1 | 5.2 | No |
| 407558 |  CHEMBL1253499 | C33H32Cl3N3O4 | 640.986 | 5 / 1 | N/A | No |
| 413300 |  CHEMBL576341 | C28H39N3O6S2 | 577.755 | 9 / 1 | 3.7 | No |
| 415858 |  CHEMBL572984 | C32H41N3O6S2 | 627.815 | 9 / 1 | 4.8 | No |
| 420912 |  CHEMBL577599 | C27H32ClN3O2S2 | 530.142 | 6 / 1 | 5.4 | No |
| 423806 |  d[Leu4,Dap8]VP | C44H61N11O11S2 | 984.158 | 14 / 11 | -1.6 | No |
| 427944 |  CHEMBL575986 | C27H32ClN3O4S3 | 594.2 | 8 / 1 | 4.7 | No |
| 430962 |  CHEMBL575574 | C28H32ClN3O3S2 | 558.152 | 6 / 1 | 4.8 | No |
| 431077 |  d[Cha4]AVP | C50H71N13O11S2 | 1094.32 | 14 / 12 | -0.1 | No |
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