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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SSR126768A
Molecular formula	C33H31Cl2N3O4
IUPAC name	4-chloro-3-[(3R)-5-chloro-1-[(2,4-dimethoxyphenyl)methyl]-3-methyl-2-oxoindol-3-yl]-N-ethyl-N-(pyridin-3-ylmethyl)benzamide
Molecular weight	604.528
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	6.0
Synonyms	CHEMBL1615640 4-Chloro-3-[(3R)-5-chloro-1-[(2,4-dimethoxyphenyl)methyl]-2,3-dihydro-3-methyl-2-oxo-1H-indole-3-yl]-N-ethyl-N-(3-pyridylmethyl)benzamide SCHEMBL44610 BDBM50326716 (R)-4-chloro-3-(5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxoindolin-3-yl)-N-ethyl-N-(pyridin-3-ylmethyl)benzamide hydrochloride D0Q0OR 4-chloro-3-[(3R)-5-chloro-1-[(2,4-dimethoxyphenyl)methyl]-3-methyl-2-oxoindol-3-yl]-N-ethyl-N-(pyridin-3-ylmethyl)benzamide SSR-126768A CHEMBL1253499 GTPL2201 [ Show all ]
Inchi Key	UENRBNCNIZQNTR-XIFFEERXSA-N
Inchi ID	InChI=1S/C33H31Cl2N3O4/c1-5-37(19-21-7-6-14-36-18-21)31(39)22-9-12-28(35)26(15-22)33(2)27-16-24(34)10-13-29(27)38(32(33)40)20-23-8-11-25(41-3)17-30(23)42-4/h6-18H,5,19-20H2,1-4H3/t33-/m0/s1
PubChem CID	10461270
ChEMBL	N/A
IUPHAR	2201
BindingDB	50326716
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
334892	Oxytocin receptor	P70536	Oxtr	Rattus norvegicus (Rat)	388
334894	Oxytocin receptor	P30559	OXTR	Homo sapiens (Human)	389
334889	Vasopressin V1a receptor	P37288	AVPR1A	Homo sapiens (Human)	418
334895	Vasopressin V1a receptor	P30560	Avpr1a	Rattus norvegicus (Rat)	424
334891	Vasopressin V1b receptor	P48974	Avpr1b	Rattus norvegicus (Rat)	425
334890	Vasopressin V2 receptor	Q00788	Avpr2	Rattus norvegicus (Rat)	371
334893	Vasopressin V2 receptor	P30518	AVPR2	Homo sapiens (Human)	371

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