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Name | Oxytocin receptor |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Oxtr |
Synonym | OT receptor OT-R OTR |
Disease | N/A for non-human GPCRs |
Length | 388 |
Amino acid sequence | MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDVNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETSVSKKSNSSTFVLSRRSSSQRSCSQPSSA |
UniProt | P70536 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3996 |
IUPHAR | 369 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
243 | CHEMBL341267 | C23H29NO3S | 399.549 | 4 / 0 | 3.7 | Yes |
244 | CHEMBL126962 | C23H29NO3S | 399.549 | 4 / 0 | 3.7 | Yes |
246 | CHEMBL420144 | C23H29NO3S | 399.549 | 4 / 0 | 3.7 | Yes |
1831 | CHEMBL128328 | C26H39N3O3S | 473.676 | 5 / 2 | 3.6 | Yes |
2143 | CHEMBL1790547 | C40H48N8O6 | 736.874 | 8 / 2 | 3.0 | No |
3444 | [Pip7]OT | C44H68N12O12S2 | 1021.22 | 15 / 12 | -2.2 | No |
8709 | CHEMBL337976 | C20H20N2O | 304.393 | 1 / 1 | 3.9 | Yes |
9476 | CHEMBL340639 | C27H42N4O5S2 | 566.776 | 8 / 3 | 2.3 | No |
10252 | CID 10029477 | C27H38N4O4S | 514.685 | 6 / 2 | 3.3 | No |
11564 | CHEMBL336082 | C33H46N6O5S | 638.828 | 7 / 4 | 2.4 | No |
11607 | CID 10393379 | C32H40N4O4S | 576.756 | 6 / 1 | 4.6 | No |
12064 | CHEMBL131499 | C25H32N2O3S | 440.602 | 5 / 1 | 4.1 | Yes |
12065 | CHEMBL127049 | C25H32N2O3S | 440.602 | 5 / 1 | 4.1 | Yes |
12334 | CHEMBL3277915 | C41H63N11O12S2 | 966.14 | 14 / 12 | -2.1 | No |
12880 | CHEMBL143341 | C25H30N4O4 | 450.539 | 4 / 2 | 2.0 | Yes |
13170 | CHEMBL338018 | C46H61N7O6 | 808.037 | 7 / 4 | 5.1 | No |
14871 | CHEMBL385062 | C51H73N13O10S2 | 1092.35 | 13 / 11 | 0.1 | No |
14874 | CHEMBL266643 | C51H73N13O10S2 | 1092.35 | 13 / 11 | 0.1 | No |
442222 | CHEMBL3350125 | C51H73N13O10S2 | 1092.35 | 13 / 11 | 0.1 | No |
17423 | CHEMBL129089 | C43H58N6O6 | 754.973 | 6 / 2 | 5.1 | No |
18635 | CHEMBL1790550 | C40H52N8O5 | 724.907 | 8 / 2 | 3.0 | No |
19940 | CHEMBL339493 | C36H52N6O6 | 664.848 | 6 / 2 | 3.2 | No |
21634 | [Mpa1, D-Tic7]OT | C48H67N11O12S2 | 1054.25 | 14 / 11 | -0.7 | No |
21637 | [Mpa1, L-Tic7]OT | C48H67N11O12S2 | 1054.25 | 14 / 11 | -0.7 | No |
22596 | CHEMBL3277916 | C40H61N11O12S2 | 952.113 | 14 / 12 | -2.5 | No |
22762 | CHEMBL335886 | C34H48N3O6S+ | 626.833 | 7 / 2 | 3.9 | No |
24394 | CHEMBL340531 | C24H31NO4S | 429.575 | 5 / 0 | 3.7 | Yes |
24468 | CHEMBL339450 | C42H54N8O6 | 766.944 | 7 / 4 | 3.9 | No |
24491 | CHEMBL1790201 | C43H63N11O12S2 | 990.162 | 14 / 11 | -2.2 | No |
26351 | BDBM50043061 | C31H39N3O5S | 565.729 | 6 / 3 | 3.7 | No |
28254 | CHEMBL129498 | C23H28FNO3S | 417.539 | 5 / 0 | 3.8 | Yes |
30078 | CHEMBL429161 | C47H74N12O12S2 | 1063.3 | 15 / 12 | -0.8 | No |
32105 | CHEMBL3229638 | C46H71N11O12S2 | 1034.26 | 14 / 10 | -0.8 | No |
32199 | CHEMBL441128 | C46H73N11O12S2 | 1036.28 | 14 / 11 | 0.0 | No |
36182 | CHEMBL558950 | C57H77N13O10S2 | 1168.44 | 13 / 11 | 1.5 | No |
36184 | CHEMBL558950 | C57H77N13O10S2 | 1168.44 | 13 / 11 | 1.5 | No |
37056 | d[Cha4,Orn8]VP | C49H69N11O11S2 | 1052.28 | 14 / 11 | 0.5 | No |
38952 | CHEMBL131477 | C33H47N5O6S2 | 673.888 | 8 / 3 | 3.0 | No |
39034 | CHEMBL128398 | C28H38N4O3S | 510.697 | 5 / 1 | 4.0 | No |
39221 | CHEMBL105514 | C28H28FN3O6 | 521.545 | 7 / 0 | 2.8 | No |
39653 | CHEMBL339151 | C26H36N2O4S | 472.644 | 5 / 2 | 3.2 | Yes |
40891 | CHEMBL341108 | C19H18FNO2S | 343.416 | 4 / 0 | 3.9 | Yes |
42484 | CID 10415322 | C29H40N4O5S | 556.722 | 6 / 2 | 2.9 | No |
43066 | CHEMBL340153 | C29H35NO3S | 477.663 | 4 / 1 | 5.3 | No |
43958 | BDBM50043148 | C32H43N5O4S | 593.787 | 6 / 1 | 4.0 | No |
44503 | CHEMBL128388 | C28H41N3O3S | 499.714 | 5 / 1 | 4.0 | Yes |
44555 | CHEMBL115277 | C25H28O8 | 456.491 | 8 / 0 | 4.4 | Yes |
44754 | CHEMBL2369831 | C45H63N13O12S2 | 1042.2 | 15 / 13 | -2.9 | No |
44763 | CHEMBL3277498 | C45H63N13O12S2 | 1042.2 | 15 / 13 | -2.9 | No |
46798 | CHEMBL417458 | C31H46N4O4S | 570.793 | 7 / 1 | 3.4 | No |
51467 | CHEMBL339155 | C31H47N3O3S | 541.795 | 5 / 2 | 4.7 | No |
51474 | CHEMBL129647 | C21H21NO2 | 319.404 | 2 / 0 | 4.1 | Yes |
51906 | CHEMBL291005 | C44H67N11O12S2 | 1006.21 | 14 / 11 | -1.0 | No |
51907 | CHEMBL2372251 | C44H67N11O12S2 | 1006.21 | 14 / 11 | -1.0 | No |
52720 | CHEMBL336195 | C27H39N3O3S | 485.687 | 5 / 1 | 3.5 | Yes |
53307 | CID 10051081 | C26H35N3O4S | 485.643 | 5 / 1 | 3.7 | Yes |
53745 | d[Leu4]AVP | C47H67N13O11S2 | 1054.25 | 14 / 12 | -1.5 | No |
54085 | CHEMBL306010 | C35H42N4O6 | 614.743 | 7 / 0 | 4.1 | No |
54423 | CHEMBL419603 | C24H25NO2S | 391.529 | 3 / 0 | 5.3 | No |
54583 | CHEMBL2112898 | C27H44N4O5S2 | 568.792 | 8 / 2 | 2.6 | No |
54589 | CHEMBL2391300 | C27H44N4O5S2 | 568.792 | 8 / 2 | 2.6 | No |
55576 | CHEMBL394411 | C45H70N12O12S2 | 1035.25 | 15 / 11 | -1.9 | No |
55591 | CHEMBL128652 | C33H46N6O5S | 638.828 | 7 / 4 | 2.4 | No |
55835 | CHEMBL2372955 | C40H54N8O6 | 742.922 | 8 / 4 | 2.7 | No |
55911 | CHEMBL338503 | C30H40N2O6S | 556.718 | 7 / 1 | 3.6 | No |
57488 | BDBM50043141 | C29H40N8O4S | 596.751 | 9 / 5 | 3.3 | No |
57666 | CHEMBL302297 | C34H40N4O6 | 600.716 | 7 / 0 | 3.7 | No |
60339 | CHEMBL262157 | C50H77N15O11S2 | 1128.38 | 14 / 15 | -2.1 | No |
60747 | CHEMBL208787 | C30H35N3O4 | 501.627 | 4 / 2 | 5.1 | No |
62558 | CHEMBL274955 | C24H34N2O3S | 430.607 | 5 / 2 | 2.9 | Yes |
62559 | CHEMBL128124 | C24H34N2O3S | 430.607 | 5 / 2 | 2.9 | Yes |
63103 | CHEMBL126883 | C21H25NO4S | 387.494 | 5 / 0 | 3.6 | Yes |
63820 | CHEMBL131269 | C30H39N3O3S | 521.72 | 5 / 1 | 4.6 | No |
63938 | CHEMBL129708 | C19H18N2O4S | 370.423 | 5 / 0 | 3.7 | Yes |
65998 | d[Cha4,Dab8]VP | C48H67N11O11S2 | 1038.25 | 14 / 11 | 0.1 | No |
69265 | CHEMBL127119 | C24H30N2O | 362.517 | 1 / 1 | 4.7 | Yes |
69341 | CHEMBL232501 | C46H73N11O12S2 | 1036.28 | 14 / 11 | 0.0 | No |
444452 | CHEMBL3349464 | C46H68N10O11S2 | 1001.23 | 14 / 11 | -1.4 | No |
444456 | CHEMBL3349466 | C46H68N10O11S2 | 1001.23 | 14 / 11 | -1.4 | No |
70863 | CHEMBL1790307 | C46H68N10O11S2 | 1001.23 | 14 / 11 | -1.4 | No |
70867 | CHEMBL1790312 | C46H68N10O11S2 | 1001.23 | 14 / 11 | -1.4 | No |
71354 | CHEMBL338409 | C28H39NO5S | 501.682 | 6 / 1 | 5.2 | No |
71834 | CHEMBL1790938 | C41H55N9O6 | 769.948 | 7 / 4 | 3.1 | No |
72468 | CHEMBL339093 | C21H29NO3S | 375.527 | 4 / 1 | 3.4 | Yes |
74001 | CHEMBL406533 | C53H73N11O11S2 | 1104.35 | 13 / 8 | 0.6 | No |
74045 | CHEMBL339464 | C36H50N2O4S | 606.866 | 5 / 2 | 6.6 | No |
444712 | CHEMBL3350126 | C48H74N12O12S2 | 1075.31 | 15 / 11 | -1.9 | No |
76268 | CHEMBL261914 | C48H74N12O12S2 | 1075.31 | 15 / 11 | -1.9 | No |
76270 | CHEMBL263521 | C48H74N12O12S2 | 1075.31 | 15 / 11 | -1.9 | No |
76404 | d[Arg4,Orn8]VP | C46H66N14O11S2 | 1055.24 | 15 / 13 | -3.4 | No |
76519 | CHEMBL131388 | C29H43N3O6S2 | 593.798 | 8 / 3 | 2.0 | No |
76615 | CHEMBL24456 | C32H38F3N3O5 | 601.667 | 9 / 0 | 5.3 | No |
76679 | CHEMBL2112663 | C28H43N3O6S2 | 581.787 | 8 / 3 | 1.7 | No |
76754 | CHEMBL263153 | C50H76N14O12S2 | 1129.36 | 15 / 15 | -1.4 | No |
76755 | CHEMBL274635 | C50H76N14O12S2 | 1129.36 | 15 / 15 | -1.4 | No |
76756 | CHEMBL414373 | C50H76N14O12S2 | 1129.36 | 15 / 15 | -1.4 | No |
76757 | CHEMBL386547 | C50H76N14O12S2 | 1129.36 | 15 / 15 | -1.4 | No |
76758 | CHEMBL268779 | C50H76N14O12S2 | 1129.36 | 15 / 15 | -1.4 | No |
76759 | CHEMBL268778 | C50H76N14O12S2 | 1129.36 | 15 / 15 | -1.4 | No |
76760 | CHEMBL439482 | C50H76N14O12S2 | 1129.36 | 15 / 15 | -1.4 | No |
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