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| Name | Vasopressin V2 receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Avpr2 |
| Synonym | AVPR V2 Antidiuretic hormone receptor ADHR Renal-type arginine vasopressin receptor V2 receptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 371 |
| Amino acid sequence | MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLGALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGPSERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCATASSSLMKDTPS |
| UniProt | Q00788 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3766 |
| IUPHAR | 368 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 245 |  CHEMBL420144 | C23H29NO3S | 399.549 | 4 / 0 | 3.7 | Yes |
| 1830 |  CHEMBL128328 | C26H39N3O3S | 473.676 | 5 / 2 | 3.6 | Yes |
| 2142 |  CHEMBL1790547 | C40H48N8O6 | 736.874 | 8 / 2 | 3.0 | No |
| 6000 |  CHEMBL2371240 | C44H65N15O11S2 | 1044.22 | 14 / 12 | -4.4 | No |
| 6297 |  CHEMBL2370378 | C63H97N17O11 | 1268.58 | 14 / 14 | 0.8 | No |
| 9475 |  CHEMBL340639 | C27H42N4O5S2 | 566.776 | 8 / 3 | 2.3 | No |
| 9488 |  CHEMBL332060 | C24H22N2O3 | 386.451 | 3 / 1 | 4.2 | Yes |
| 10251 |  CID 10029477 | C27H38N4O4S | 514.685 | 6 / 2 | 3.3 | No |
| 10274 |  CHEMBL368818 | C38H42N4O4S | 650.838 | 6 / 1 | 5.8 | No |
| 11563 |  CHEMBL336082 | C33H46N6O5S | 638.828 | 7 / 4 | 2.4 | No |
| 11581 |  CHEMBL175930 | C29H26N2O3S | 482.598 | 4 / 1 | 5.8 | No |
| 11608 |  CID 10393379 | C32H40N4O4S | 576.756 | 6 / 1 | 4.6 | No |
| 12063 |  CHEMBL131499 | C25H32N2O3S | 440.602 | 5 / 1 | 4.1 | Yes |
| 12634 |  CHEMBL72945 | C28H22N2O2 | 418.496 | 2 / 1 | 5.3 | No |
| 12879 |  CHEMBL143341 | C25H30N4O4 | 450.539 | 4 / 2 | 2.0 | Yes |
| 13171 |  CHEMBL338018 | C46H61N7O6 | 808.037 | 7 / 4 | 5.1 | No |
| 14872 |  CHEMBL385062 | C51H73N13O10S2 | 1092.35 | 13 / 11 | 0.1 | No |
| 14876 |  CHEMBL266643 | C51H73N13O10S2 | 1092.35 | 13 / 11 | 0.1 | No |
| 442220 |  CHEMBL3350125 | C51H73N13O10S2 | 1092.35 | 13 / 11 | 0.1 | No |
| 16218 |  CHEMBL515607 | C28H36N4O4 | 492.62 | 4 / 1 | 2.8 | Yes |
| 17103 |  CHEMBL2373370 | C52H81N13O10 | 1048.3 | 12 / 11 | 0.9 | No |
| 17425 |  CHEMBL129089 | C43H58N6O6 | 754.973 | 6 / 2 | 5.1 | No |
| 17817 |  CHEMBL350090 | C24H19FN4O2S | 446.5 | 5 / 2 | 3.9 | Yes |
| 18418 |  CHEMBL159856 | C28H23ClN2O2S | 487.014 | 3 / 1 | 6.8 | No |
| 18634 |  CHEMBL1790550 | C40H52N8O5 | 724.907 | 8 / 2 | 3.0 | No |
| 19941 |  CHEMBL339493 | C36H52N6O6 | 664.848 | 6 / 2 | 3.2 | No |
| 20111 |  CHEMBL75489 | C40H42N6O4 | 670.814 | 6 / 1 | 5.5 | No |
| 22493 |  CHEMBL2373551 | C58H85N19O11 | 1224.44 | 14 / 16 | -2.3 | No |
| 22763 |  CHEMBL335886 | C34H48N3O6S+ | 626.833 | 7 / 2 | 3.9 | No |
| 23743 |  CHEMBL2370641 | C50H73N9O9S2 | 1008.31 | 12 / 8 | 3.4 | No |
| 24467 |  CHEMBL339450 | C42H54N8O6 | 766.944 | 7 / 4 | 3.9 | No |
| 26192 |  CHEMBL2373423 | C53H75N13O10 | 1054.26 | 12 / 11 | 0.4 | No |
| 26352 |  BDBM50043061 | C31H39N3O5S | 565.729 | 6 / 3 | 3.7 | No |
| 27012 |  CHEMBL76763 | C37H40N4O5 | 620.75 | 6 / 1 | 5.7 | No |
| 27366 |  CHEMBL332685 | C25H25N3O2 | 399.494 | 3 / 1 | 4.4 | Yes |
| 28089 |  CHEMBL59896 | C22H24N2O2 | 348.446 | 2 / 0 | 3.3 | Yes |
| 28140 |  CHEMBL418692 | C26H33N3O3 | 435.568 | 4 / 1 | 3.1 | Yes |
| 29226 |  CHEMBL333139 | C23H20N2O2 | 356.425 | 2 / 1 | 4.2 | Yes |
| 29779 |  CHEMBL119551 | C23H19ClN2O2 | 390.867 | 2 / 1 | 4.8 | Yes |
| 32171 |  CHEMBL405055 | C56H83N17O12S2 | 1250.51 | 16 / 14 | -3.0 | No |
| 32340 |  CHEMBL331956 | C18H18N2O2 | 294.354 | 2 / 1 | 2.5 | Yes |
| 32456 |  CHEMBL59947 | C21H22N2O2 | 334.419 | 2 / 0 | 3.0 | Yes |
| 32564 |  CHEMBL64046 | C23H24N2O4 | 392.455 | 4 / 0 | 2.7 | Yes |
| 32597 |  CHEMBL117566 | C25H24N2O2 | 384.479 | 2 / 1 | 4.9 | Yes |
| 33167 |  CHEMBL405434 | C53H76N14O12S2 | 1165.4 | 15 / 12 | -1.8 | No |
| 34300 |  CHEMBL455699 | C26H25F2N3O2 | 449.502 | 4 / 2 | 4.8 | Yes |
| 36646 |  CHEMBL333201 | C24H22N2O2 | 370.452 | 2 / 1 | 4.5 | Yes |
| 37055 |  d[Cha4,Orn8]VP | C49H69N11O11S2 | 1052.28 | 14 / 11 | 0.5 | No |
| 38299 |  CHEMBL177248 | C37H44N4O3S | 624.844 | 6 / 1 | 6.6 | No |
| 38953 |  CHEMBL131477 | C33H47N5O6S2 | 673.888 | 8 / 3 | 3.0 | No |
| 39033 |  CHEMBL128398 | C28H38N4O3S | 510.697 | 5 / 1 | 4.0 | No |
| 39048 |  CHEMBL3037878 | C52H76N10O10S2 | 1065.36 | 13 / 9 | 2.8 | No |
| 39652 |  CHEMBL339151 | C26H36N2O4S | 472.644 | 5 / 2 | 3.2 | Yes |
| 39750 |  Relcovaptan | C28H27Cl2N3O7S | 620.498 | 8 / 2 | 3.8 | No |
| 40101 |  CHEMBL159823 | C32H25N3O2 | 483.571 | 2 / 1 | 5.3 | No |
| 42175 |  CHEMBL2373510 | C60H89N17O11 | 1224.48 | 14 / 14 | -0.7 | No |
| 42485 |  CID 10415322 | C29H40N4O5S | 556.722 | 6 / 2 | 2.9 | No |
| 43957 |  BDBM50043148 | C32H43N5O4S | 593.787 | 6 / 1 | 4.0 | No |
| 44502 |  CHEMBL128388 | C28H41N3O3S | 499.714 | 5 / 1 | 4.0 | Yes |
| 45731 |  CHEMBL437035 | C59H80N14O13S2 | 1257.49 | 16 / 13 | -0.6 | No |
| 46147 |  CHEMBL2370640 | C54H79N13O11S2 | 1150.43 | 14 / 11 | 1.1 | No |
| 46800 |  CHEMBL417458 | C31H46N4O4S | 570.793 | 7 / 1 | 3.4 | No |
| 51468 |  CHEMBL339155 | C31H47N3O3S | 541.795 | 5 / 2 | 4.7 | No |
| 52719 |  CHEMBL336195 | C27H39N3O3S | 485.687 | 5 / 1 | 3.5 | Yes |
| 53308 |  CID 10051081 | C26H35N3O4S | 485.643 | 5 / 1 | 3.7 | Yes |
| 53746 |  d[Leu4]AVP | C47H67N13O11S2 | 1054.25 | 14 / 12 | -1.5 | No |
| 54211 |  CHEMBL175211 | C28H25N3O2 | 435.527 | 2 / 2 | 5.0 | Yes |
| 54581 |  CHEMBL2112898 | C27H44N4O5S2 | 568.792 | 8 / 2 | 2.6 | No |
| 54587 |  CHEMBL2391300 | C27H44N4O5S2 | 568.792 | 8 / 2 | 2.6 | No |
| 54624 |  CHEMBL119591 | C27H27N3O3 | 441.531 | 3 / 2 | 3.8 | Yes |
| 55592 |  CHEMBL128652 | C33H46N6O5S | 638.828 | 7 / 4 | 2.4 | No |
| 55836 |  CHEMBL2372955 | C40H54N8O6 | 742.922 | 8 / 4 | 2.7 | No |
| 55910 |  CHEMBL338503 | C30H40N2O6S | 556.718 | 7 / 1 | 3.6 | No |
| 56284 |  CHEMBL64695 | C25H30N2O3 | 406.526 | 3 / 0 | 4.2 | Yes |
| 57489 |  BDBM50043141 | C29H40N8O4S | 596.751 | 9 / 5 | 3.3 | No |
| 61655 |  CHEMBL442743 | C26H20FN3O2 | 425.463 | 3 / 1 | 3.8 | Yes |
| 62543 |  CHEMBL59397 | C22H23N3O3 | 377.444 | 3 / 1 | 1.8 | Yes |
| 62557 |  CHEMBL274955 | C24H34N2O3S | 430.607 | 5 / 2 | 2.9 | Yes |
| 62560 |  CHEMBL128124 | C24H34N2O3S | 430.607 | 5 / 2 | 2.9 | Yes |
| 63498 |  CHEMBL334082 | C27H29N3O3 | 443.547 | 4 / 1 | 4.1 | Yes |
| 63821 |  CHEMBL131269 | C30H39N3O3S | 521.72 | 5 / 1 | 4.6 | No |
| 65501 |  CHEMBL308741 | C29H24N2O2 | 432.523 | 2 / 1 | 5.8 | No |
| 65700 |  CHEMBL311230 | C26H18Cl3N3O2 | 510.799 | 2 / 1 | 5.6 | No |
| 65996 |  d[Cha4,Dab8]VP | C48H67N11O11S2 | 1038.25 | 14 / 11 | 0.1 | No |
| 67114 |  CHEMBL387273 | C51H74N12O10S2 | 1079.35 | 13 / 10 | 1.1 | No |
| 67117 |  CHEMBL384776 | C51H74N12O10S2 | 1079.35 | 13 / 10 | 1.1 | No |
| 67335 |  CHEMBL262482 | C52H76N12O10S2 | 1093.37 | 13 / 10 | 1.3 | No |
| 67991 |  CHEMBL347020 | C28H23ClN2O2S | 487.014 | 3 / 1 | 6.5 | No |
| 68194 |  CHEMBL121455 | C23H19ClN2O2 | 390.867 | 2 / 1 | 4.8 | Yes |
| 68775 |  CHEMBL119318 | C26H25Cl2N3O2 | 482.405 | 3 / 1 | 5.4 | No |
| 69303 |  CHEMBL264513 | C54H79N15O12S2 | 1194.44 | 16 / 13 | -2.7 | No |
| 70069 |  CHEMBL60096 | C27H33N3O4 | 463.578 | 4 / 1 | 3.0 | Yes |
| 444453 |  CHEMBL3349464 | C46H68N10O11S2 | 1001.23 | 14 / 11 | -1.4 | No |
| 444454 |  CHEMBL3349466 | C46H68N10O11S2 | 1001.23 | 14 / 11 | -1.4 | No |
| 70864 |  CHEMBL1790307 | C46H68N10O11S2 | 1001.23 | 14 / 11 | -1.4 | No |
| 71833 |  CHEMBL1790938 | C41H55N9O6 | 769.948 | 7 / 4 | 3.1 | No |
| 72626 |  CHEMBL175411 | C28H24N2O3 | 436.511 | 3 / 1 | 5.3 | No |
| 73502 |  CHEMBL2373516 | C54H77N13O10 | 1068.29 | 12 / 11 | 0.8 | No |
| 73576 |  CHEMBL299440 | C28H26N4O5 | 498.539 | 6 / 1 | 2.9 | Yes |
| 74044 |  CHEMBL339464 | C36H50N2O4S | 606.866 | 5 / 2 | 6.6 | No |
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