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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL75489
Molecular formula	C40H42N6O4
IUPAC name	2-(2-ethylimidazol-1-yl)-N-[4-[methyl-[4-methyl-2-[[4-(4-methylpiperazine-1-carbonyl)phenyl]methoxy]phenyl]carbamoyl]phenyl]benzamide
Molecular weight	670.814
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.5
Synonyms	BDBM50108499 1N-methyl-1N-{4-methyl-2-[4-(4-methylhexahydro-1-pyrazinylcarbonyl)benzyloxy]phenyl}-4-[2-(2-ethyl-1H-1-imidazolyl)phenylcarboxamido]benzamide
Inchi Key	BCEZGQLWWKMCIT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C40H42N6O4/c1-5-37-41-20-21-46(37)34-9-7-6-8-33(34)38(47)42-32-17-15-30(16-18-32)39(48)44(4)35-19-10-28(2)26-36(35)50-27-29-11-13-31(14-12-29)40(49)45-24-22-43(3)23-25-45/h6-21,26H,5,22-25,27H2,1-4H3,(H,42,47)
PubChem CID	44313913
ChEMBL	CHEMBL75489
IUPHAR	N/A
BindingDB	50108499
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20112	Vasopressin V1a receptor	P30560	Avpr1a	Rattus norvegicus (Rat)	424
20111	Vasopressin V2 receptor	Q00788	Avpr2	Rattus norvegicus (Rat)	371

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