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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Vasopressin V2 receptor
Species	Rattus norvegicus (Rat)
Gene	Avpr2
Synonym	AVPR V2 Antidiuretic hormone receptor ADHR Renal-type arginine vasopressin receptor V2 receptor V2R DIR3 [ Show all ]
Disease	N/A for non-human GPCRs
Length	371
Amino acid sequence	MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLGALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGPSERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCATASSSLMKDTPS
UniProt	Q00788
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3766
IUPHAR	368
DrugBank	N/A

Ligand

Name	CHEMBL59947
Molecular formula	C21H22N2O2
IUPAC name	1-(1-benzoylpiperidin-4-yl)-3,4-dihydroquinolin-2-one
Molecular weight	334.419
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	3.0
Synonyms	BTMDANAHCWMZKX-UHFFFAOYSA-N SCHEMBL7290744 1-(1-benzoyl-4-piperidinyl)-3,4-dihydrocarbostyril 1-(1-Benzoyl-piperidin-4-yl)-3,4-dihydro-1H-quinolin-2-one BDBM50045133 1-[1-Benzoyl-4-piperidinyl]-3,4-dihydro-2(1H)-quinolone [ Show all ]
Inchi Key	BTMDANAHCWMZKX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22N2O2/c24-20-11-10-16-6-4-5-9-19(16)23(20)18-12-14-22(15-13-18)21(25)17-7-2-1-3-8-17/h1-9,18H,10-15H2
PubChem CID	14969510
ChEMBL	CHEMBL59947
IUPHAR	N/A
BindingDB	50045133
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<50000.0 nM	PMID8393113	BindingDB,ChEMBL

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