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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Vasopressin V2 receptor
Species	Rattus norvegicus (Rat)
Gene	Avpr2
Synonym	AVPR V2 Antidiuretic hormone receptor ADHR Renal-type arginine vasopressin receptor V2 receptor V2R DIR3 [ Show all ]
Disease	N/A for non-human GPCRs
Length	371
Amino acid sequence	MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLGALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGPSERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCATASSSLMKDTPS
UniProt	Q00788
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3766
IUPHAR	368
DrugBank	N/A

Ligand

Name	CHEMBL331956
Molecular formula	C18H18N2O2
IUPAC name	N-[4-(3,4-dihydro-2H-quinoline-1-carbonyl)phenyl]acetamide
Molecular weight	294.354
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	2.5
Synonyms	AC1LDM5T HMS2848B15 Oprea1_490479 BDBM50052917 MolPort-001-508-345 SR-01000426153 N-[4-(3,4-dihydro-2H-quinoline-1-carbonyl)phenyl]acetamide STK076695 AKOS000678156 MCULE-5180066320 Oprea1_834200 BIM-0029123.P001 N-[4-(1,2,3,4-tetrahydroquinolylcarbonyl)phenyl]acetamide SR-01000426153-1 AB00094979-01 N-[4-(3,4-dihydroquinolin-1(2H)-ylcarbonyl)phenyl]acetamide ZINC30071 BAS 00854680 MLS001204603 SMR000515579 CBMicro_029259 N-[4-(3,4-Dihydro-2H-quinoline-1-carbonyl)-phenyl]-acetamide ST043120 [ Show all ]
Inchi Key	BTHHYGOCYRAYLZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H18N2O2/c1-13(21)19-16-10-8-15(9-11-16)18(22)20-12-4-6-14-5-2-3-7-17(14)20/h2-3,5,7-11H,4,6,12H2,1H3,(H,19,21)
PubChem CID	669479
ChEMBL	CHEMBL331956
IUPHAR	N/A
BindingDB	50052917
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<100000.0 nM	PMID8784453	BindingDB,ChEMBL

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