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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	DESMOPRESSIN
Molecular formula	C46H64N14O12S2
IUPAC name	(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Molecular weight	1069.22
Hydrogen bond acceptor	15
Hydrogen bond donor	13
XlogP	-4.0
Synonyms	DSSTox_GSID_48259 DB00035 NCGC00181133-02 (S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((S)-1-(2-amino-2-oxoethylamino)-5-guanidino-1-oxopentan-2-yl)pyrrol Desmopressinum BDBM50205291 CHEMBL376685 DSSTox_RID_82746 deamino-[Cys1]arginine vasopressin SCHEMBL22510 1-Desamino-8-D-arginine vasopressin DSSTox_CID_28234 CAS-16679-58-6 DTXSID1048259 Tox21_113379 [ Show all ]
Inchi Key	NFLWUMRGJYTJIN-NXBWRCJVSA-N
Inchi ID	InChI=1S/C46H64N14O12S2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52)/t28-,29-,30-,31-,32-,33-,34-/m0/s1
PubChem CID	16051933
ChEMBL	CHEMBL376685
IUPHAR	N/A
BindingDB	50205291
DrugBank	DB00035
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
222045	Oxytocin receptor	P70536	Oxtr	Rattus norvegicus (Rat)	388
222046	Oxytocin receptor	P30559	OXTR	Homo sapiens (Human)	389
222048	Vasopressin V1a receptor	P30560	Avpr1a	Rattus norvegicus (Rat)	424
222052	Vasopressin V1a receptor	P37288	AVPR1A	Homo sapiens (Human)	418
222047	Vasopressin V1b receptor	P47901	AVPR1B	Homo sapiens (Human)	424
222051	Vasopressin V1b receptor	P48974	Avpr1b	Rattus norvegicus (Rat)	425
222049	Vasopressin V2 receptor	P30518	AVPR2	Homo sapiens (Human)	371
222050	Vasopressin V2 receptor	Q00788	Avpr2	Rattus norvegicus (Rat)	371

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