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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL470432
Molecular formula	C19H25N3OS
IUPAC name	3-methyl-8-[(1-propylpiperidin-4-yl)methoxy]-5-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaene
Molecular weight	343.489
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.2
Synonyms	BDBM50293279 1-Methyl-5-[(1-propylpiperidin-4-yl)methyloxy]-pyrrolo[1,2-a]thieno[2,3-e]pyrazine
Inchi Key	FZGWDCDUMFWUEO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H25N3OS/c1-3-8-21-10-6-15(7-11-21)12-23-18-16-5-4-9-22(16)17-14(2)13-24-19(17)20-18/h4-5,9,13,15H,3,6-8,10-12H2,1-2H3
PubChem CID	42636941
ChEMBL	CHEMBL470432
IUPHAR	N/A
BindingDB	50293279
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
90898	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
90894	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
90903	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374
90896	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
90897	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
90901	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
90891	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
90900	5-hydroxytryptamine receptor 4	P97288	Htr4	Mus musculus (Mouse)	388
90905	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
90892	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
90899	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
90906	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
90893	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
90902	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
90907	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
90895	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
90904	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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