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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SDZ-205557
Molecular formula	C14H21ClN2O3
IUPAC name	2-(diethylamino)ethyl 4-amino-5-chloro-2-methoxybenzoate
Molecular weight	300.783
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.2
Synonyms	D0W8EP NCGC00015916-01 SCHEMBL1038983 2-(Diethylamino)ethyl 4-amino-5-chloro-2-methoxybenzoate AC1L1JSU BPBio1_000574 CCG-205227 L001009 NCGC00015916-05 SDZ 205557 2-methoxy-4-amino-5-chloro-benzoic acid 2-(diethylamino) ethyl ester AKOS030238974 CHEMBL287045 LS-186950 PDSP1_001668 ZINC1544798 4-Amino-5-chloro-2-methoxy-benzoic acid 2-diethylamino-ethyl ester Benzoic acid,4-amino-5-chloro-2-methoxy-, 2-(diethylamino)ethyl ester DTXSID90160102 NCGC00015916-03 Sdz 205,557 2-diethylaminoethyl 4-amino-5-chloro-2-methoxybenzoate AC1Q3LU5 BRD-K15868788-001-01-4 CHEBI:92288 Lopac-S-174 NCGC00092301-02 SDZ-205-557 2-Methoxy-4-amino-5-chlorobenzoic acid 2-(diethylamino)ethyl ester BDBM50056401 CTK4C0686 LS-187597 PDSP2_001652 137196-67-9 Biomol-NT_000157 GTPL258 NCGC00015916-04 SDZ 205-557 2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]benzoate ACMC-20cut4 BRD-K15868788-003-02-8 Lopac0_001153 NCGC00092301-03 Benzoic acid, 4-amino-5-chloro-2-methoxy-, 2-(diethylamino)ethyl ester [ Show all ]
Inchi Key	FFNWMBDISAYHDC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H21ClN2O3/c1-4-17(5-2)6-7-20-14(18)10-8-11(15)12(16)9-13(10)19-3/h8-9H,4-7,16H2,1-3H3
PubChem CID	5191
ChEMBL	CHEMBL287045
IUPHAR	258
BindingDB	50056401
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555771	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
77260	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
77262	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
77263	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
553655	5-hydroxytryptamine receptor 4	P97288	Htr4	Mus musculus (Mouse)	388
77261	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
77264	Alpha-2A adrenergic receptor	Q28838	ADRA2A	Bos taurus (Bovine)	452
77267	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
77266	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
77268	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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