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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-QPE81T4KH0
Molecular formula	C23H32FN3O4
IUPAC name	6-fluoro-N-[[1-[(4-hydroxyoxan-4-yl)methyl]piperidin-4-yl]methyl]-3,3-dimethyl-2-oxoindole-1-carboxamide
Molecular weight	433.524
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.5
Synonyms	DB12949 QPE81T4KH0 CHEMBL2179582 1400811-63-3 PF-03227077 BDBM50398588 D01ABX 1H-Indole-1-carboxamide, 6-fluoro-2,3-dihydro-3,3-dimethyl-2-oxo-N-((1-((tetrahydro-4-hydroxy-2H-pyran-4-yl)methyl)-4-piperidinyl)methyl)- PF-03382792 [ Show all ]
Inchi Key	AGMOFKKOVMRGAK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H32FN3O4/c1-22(2)18-4-3-17(24)13-19(18)27(20(22)28)21(29)25-14-16-5-9-26(10-6-16)15-23(30)7-11-31-12-8-23/h3-4,13,16,30H,5-12,14-15H2,1-2H3,(H,25,29)
PubChem CID	71451950
ChEMBL	CHEMBL2179582
IUPHAR	N/A
BindingDB	50398588
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5019	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
5020	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406

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