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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL224935
Molecular formula	C27H34N4O
IUPAC name	6-[4-(3-cyanophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Molecular weight	430.596
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.2
Synonyms	BDBM50157783 4-(3-cyanophenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide
Inchi Key	AQGOMYFVHABIMM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H34N4O/c28-21-22-8-6-11-24(20-22)31-18-16-30(17-19-31)15-5-1-2-14-27(32)29-26-13-7-10-23-9-3-4-12-25(23)26/h3-4,6,8-9,11-12,20,26H,1-2,5,7,10,13-19H2,(H,29,32)
PubChem CID	11488153
ChEMBL	CHEMBL224935
IUPHAR	N/A
BindingDB	50157783
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11677	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
11678	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
11679	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448

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