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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL26998
Molecular formula	C16H25NO
IUPAC name	(7R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
Molecular weight	247.382
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.1
Synonyms	Lopac-H-8250 NCGC00024986-03 ZINC3870312 (7R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol(8-OH-DPAT) CCG-204725 NCGC00015493-01 R-(+)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (r)-8-hydroxy-2-(di-n-propyl-amino)tetralin AC1O7G3K FT-0641759 NCGC00024635-01 Tocris-1080 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol BRD-K59765110-004-03-8 Lopac0_000638 PDSP1_001710 (8-Hydroxyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine 8-Hydroxy-2-(di-n-propylamino)tetralin, (R)-Isomer CHEBI:103846 CTK3E5783 NCGC00015493-02 SCHEMBL1682347 (R)-8-OH-DPAT AKOS015966329 Lopac-H-140 NCGC00024986-01 UNII-IWS1724PX6 component ASXGJMSKWNBENU-CQSZACIVSA-N ((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol ((R)-OH-DPAT) C-19929 LS-177548 PDSP2_001693 (R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol 80300-09-0 DTXSID00424964 NCGC00015493-03 Tocris-0529 BDBM50016777 [ Show all ]
Inchi Key	ASXGJMSKWNBENU-CQSZACIVSA-N
Inchi ID	InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m1/s1
PubChem CID	6603866
ChEMBL	CHEMBL26998
IUPHAR	N/A
BindingDB	50016777
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13630	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
13631	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
13633	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
13632	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
13634	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
13636	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
13635	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
13638	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
13637	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
13640	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
13639	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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