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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	naphazoline
Molecular formula	C14H14N2
IUPAC name	2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole
Molecular weight	210.28
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	2.1
Synonyms	Z56762888 CNIIGCLFLJGOGP-UHFFFAOYSA-N FT-0725973 K490 KBioSS_001455 2-(1-Naphthylmethyl)-4,5-dihydro-1H-imidazole Nafazolin (TN) 2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; hydrochloride Naphazoline [INN:BAN] A840596 NCGC00016506-03 AKOS000295230 Privine (Salt/Mix) BRD-K77641333-003-15-6 Spectrum3_000513 CCG-250339 HMS1394P03 KBio2_001455 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)- MCULE-9097339235 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole Nafazoline 5-23-08-00293 (Beilstein Handbook Reference) Naphazolinum [Latin] AB00053505_13 NINDS_000456 Antan SBI-0051454.P003 BSPBio_000171 Spectrum_000975 cid_11079 EINECS 212-641-5 IMI033 KBio3_001565 2-(1-naphthalenylmethyl)-4,5-dihydro-1H-imidazole NAFAZAIR 2-(naphthylmethyl)-2-imidazoline Naphazoline (INN) 550N992 NCGC00016506-01 AJ-11616 Prestwick2_000046 BPBio1_000189 SPBio_002092 C14H14N2 T8212 ZINC119717 D08253 GTPL5509 KB-224262 L000878 2-(1-Naphthylmethyl)-4,5-dihydro-1H-imidazole # Nafazolina 2-[(naphthalen-1-yl)methyl]-4,5-dihydro-1H-imidazole Naphazolinum AB00053505-11 NCGC00016506-04 alpha-Naphthylmethyl imidazoline Rhinazine BRD-K77641333-003-25-5 Spectrum4_000068 CHEBI:93363 CHEMBL761 DB06711 HMS2090D15 KBio2_004023 2-(.alpha.-Naphthylmethyl)-imidazoline MolPort-001-641-043 2-(Naphthyl-(1')-methyl)imidazolin Nafazoline [Spanish] Naphcon AB00053505_14 Prestwick0_000046 BBL012612 SCHEMBL34532 BSPBio_002065 ST45061546 Clearine Enamine_000333 Imidin KBioGR_000595 2-(1-Naphthylmethyl)-2-imidazoline Nafazolin 2-Imidazoline, 2-(1-naphthylmethyl)- Naphazoline Monohydrochloride 835-31-4 NCGC00016506-02 AK-968/41090774 Prestwick3_000046 BRD-K77641333-003-05-7 Spectrum2_001054 CC-32429 UNII-H231GF11BV D0O6IZ H231GF11BV KBio1_000456 .alpha.-Naphthylmethyl imidazoline LS-79666 2-(alpha-Naphthylmethyl)-imidazoline Nafazolina [DCIT] 4,5-Dihydro-2-(1-naphthylmethyl)imidazole Naphazolinum [INN-Latin] AB00053505-12 NCGC00016506-05 AN-47765 Sanorin (Salt/Mix) BRN 0151864 Spectrum5_001424 CHEMBL1706 Ciba 2020/R DivK1c_000456 IDI1_000456 KBio2_006591 2-(1-Naphthalenylmethyl)-2-imidazoline Nadaplatin 2-(Naphthyl-(1')-methyl)imidazolin [German] 550-99-2 (mono-hydrochloride) Naphthizine AC1L1I5Y Prestwick1_000046 BDBM50001922 SPBio_001008 C-23907 STK300042 [ Show all ]
Inchi Key	CNIIGCLFLJGOGP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16)
PubChem CID	4436
ChEMBL	CHEMBL761
IUPHAR	N/A
BindingDB	50001922
DrugBank	DB06711
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555653	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
46052	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
555654	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
46053	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
46059	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
46054	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
46055	Alpha-2A adrenergic receptor	Q01338	Adra2a	Mus musculus (Mouse)	450
46057	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
46056	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
46058	Trace amine-associated receptor 1	Q96RJ0	TAAR1	Homo sapiens (Human)	339

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