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GLASS

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	Alpha-2A adrenergic receptor
Species	Mus musculus (Mouse)
Gene	Adra2a
Synonym	alpha2D alpha2A-AR alpha2A-adrenoceptor alpha2A-adrenergic receptor alpha2A Alpha-2AAR Alpha-2A adrenoreceptor Alpha-2A adrenoceptor adrenergic receptor Adrenergic alpha 2A receptor ADRA2R ADRA2 Adra-2a Adra-2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	450
Amino acid sequence	MGSLQPDAGNSSWNGTEAPGGGTRATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKGAGGGQQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDACSAPPGGADRRPNGLGPERGAGPTGAEAEPLPTQLNGAPGEPAPAGPRDGDALDLEESSSSEHAERPPGPRRPDRGPRAKGKTRASQVKPGDSLPRRGPGAAGPGASGSGHGEERGGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVGCPVPSQLFNFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
UniProt	Q01338
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4075
IUPHAR	N/A
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
26612	Yohimbine	C21H26N2O3	354.45	4 / 2	2.9	Yes
29585	xylazine	C12H16N2S	220.334	2 / 1	2.8	Yes
46055	naphazoline	C14H14N2	210.28	1 / 1	2.1	Yes
48561	BDBM50262235	C10H17N2O+	181.259	1 / 2	1.2	Yes
50744	levomedetomidine	C13H16N2	200.285	1 / 1	3.1	Yes
98252	clonidine	C9H9Cl2N3	230.092	1 / 2	1.6	Yes
121365	2-Methoxyidazoxan	C12H14N2O3	234.255	4 / 1	0.5	Yes
124168	xylometazoline	C16H24N2	244.382	1 / 1	3.2	Yes
128499	ST 91	C13H19N3	217.316	1 / 2	2.3	Yes
137322	GUANFACINE	C9H9Cl2N3O	246.091	1 / 2	2.0	Yes
162151	isoproterenol	C11H17NO3	211.261	4 / 4	-0.6	Yes
199641	CHEMBL7169	C13H16N2O2	232.283	3 / 3	1.1	Yes
284410	Tramazoline	C13H17N3	215.3	1 / 2	2.0	Yes
544434	norepinephrine	C8H11NO3	169.18	4 / 4	-1.2	Yes
312997	dl-Arterenol	C8H11NO3	169.18	4 / 4	-1.2	Yes
333737	AC1NJ58P	C9H13NO3	183.207	3 / 3	-0.7	Yes
335900	naphthalene	C10H8	128.174	0 / 0	3.3	Yes
385752	oxymetazoline	C16H24N2O	260.381	2 / 2	2.9	Yes
403974	brimonidine	C11H10BrN5	292.14	3 / 2	0.6	Yes

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