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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	brimonidine
Molecular formula	C11H10BrN5
IUPAC name	5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
Molecular weight	292.14
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	0.6
Synonyms	UK-14304 59803-98-4 LS-142950 [3H]-UK14304 AC-162 NCGC00016069-01 AKOS005267239 NCGC00016069-09 BRD-K68264559-001-10-0 NCGC00023468-06 BRN 0751629 SAM002548958 CHEBI:3175 TC-148557 D03ACG UK 14304 DSSTox_RID_80758 GS-3236 5-bromo-6-(2-imidazolin-2-ylamino) quinoxaline KB-197165 L000615 UNII-E6GNX3HHTE 6-Quinoxalinamine,5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)- MLS000069370 AC1Q26LW NCGC00016069-04 ARONIS24406 NCGC00016069-12 Brimonidine (bioerodible, extended release) NSC-318825 C07886 SMR000058355 cid_2435 Tox21_110299_1 D0GD9D UK-14,304-18 EN300-50880 HMS3259P09 5-bromo-6-(imidazolidinylideneamino)quinoxaline 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine Lopac0_001216 ZINC21303210 803B984 MRF-0000657 AJ-78420 NCGC00016069-07 BDBM34572 NCGC00023468-04 Brimonidine, 98% PDSP1_000640 CC-25204 SR-01000000023-4 CS-2892 UK 14,304 DSSTox_CID_25221 FT-0630717 5-bromanyl-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine HY-B0659 UK14,304 6-Quinoxalinamine, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)- MCULE-4542695850 [3H]brimonidine AC1L1DO5 NCGC00016069-02 AN-6804 NCGC00016069-10 brimonidina NCGC00023468-07 Bromoxidine SBB080815 Tocris-0425 D07540 UK 14304-18 DTXSID3045221 (5-Bromo-quinoxalin-6-yl)-(4,5-dihydro-1H-imidazol-2-yl)-amine GTPL520 5-Bromo-6-(2-imidazolin-2-ylamino)-quinoxaline KS-00000F2V LK 14304-18 XYLJNLCSTIOKRM-UHFFFAOYSA-N 6-Quinoxalinamine,5-dihydro-1H-imidazol-2-yl)- MLS001076349 AGN 190342 NCGC00016069-05 B4132 NCGC00016069-13 Brimonidine (INN) NSC318825 C11H10BrN5 SR-01000000023 CJ-16916 Tox21_501216 EU-0101216 HMS3263D14 5-Bromo-N-(2-imidazolin-2-yl)-6-quinoxalinamine UK-14,308 LP01216 ZX-AS004769 A832477 NC00638 AK-35795 NCGC00016069-08 BIDD:GT0649 NCGC00023468-05 brimonidinum PDSP2_000635 CCG-205290 ST2406733 CTK5B0525 UK 14,304-18 DSSTox_GSID_45221 FT-0650586 5-bromo-6-(2-imidazolidinylidenamino)quinoxaline IMED608142799 KS-000048KL UK14304 6-Quinoxalinamine, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)- (9CI) MFCD00153878 AC1Q24IC NCGC00016069-03 ANW-59812 NCGC00016069-11 NCGC00261901-01 C-18323 SCHEMBL24670 CHEMBL844 Tox21_110299 D0AE3X UK 14308 E6GNX3HHTE (5-bromoquinoxalin-6-yl)-2-imidazolin-2-ylamine GTPL5386 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline Lopac-U-104 Z802671510 70359-46-5 (tartrate[1:1]) MolPort-003-959-841 AGN-190342 NCGC00016069-06 BC215787 NCGC00023468-02 Brimonidine [INN:BAN] Opera_ID_612 CAS-59803-98-4 SR-01000000023-2 CPD000058355 TRA0032007 DB00484 FT-0082636 5-brom-n-(4,5-dihydro-1h-imidazol-2-yl)chinoxalin-6-amin HMS3266O03 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine [ Show all ]
Inchi Key	XYLJNLCSTIOKRM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)
PubChem CID	2435
ChEMBL	CHEMBL844
IUPHAR	520
BindingDB	34572
DrugBank	DB00484
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
403964	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
403975	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
457747	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
546861	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
403972	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
403971	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
403966	Alpha-2A adrenergic receptor	P18871	ADRA2A	Sus scrofa (Pig)	450
403968	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
403974	Alpha-2A adrenergic receptor	Q01338	Adra2a	Mus musculus (Mouse)	450
403967	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
403970	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
403973	Alpha-2B adrenergic receptor	O77715	ADRA2B	Didelphis virginiana (North American opossum)	382
403965	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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