You can:
| Name | Alpha-2B adrenergic receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Adra2b |
| Synonym | ADRA2L1 alpha2B-adrenoceptor alpha2B alpha2-C2 alpha-2BAR [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 453 |
| Amino acid sequence | MSGPTMDHQEPYSVQATAAIASAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQRPEPRGLPQCELNQEAWYILASSIGSFFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPQPVAGGVPTSAKVPTLVSPLSSVGEANGHPKPPREKEEGETPEDPEARALPPTWSALPRSGQGQKKGTSGATAEEGDEEDEEEVEECEPQTLPASPASVCNPPLQQPQTSRVLATLRGQVLLGKNVGVASGQWWRRRTQLSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICPQHCKVPHGLFQFFFWIGYCNSSLNPVIYTVFNQDFRRAFRRILCRPWTQTGW |
| UniProt | P19328 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL266 |
| IUPHAR | 26 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 3911 |  CHEMBL75491 | C12H11N5 | 225.255 | 4 / 2 | 1.6 | Yes |
| 8717 |  CHEMBL308863 | C12H15N3O2 | 233.271 | 4 / 2 | 2.2 | Yes |
| 10526 |  CHEMBL30739 | C13H16N2S | 232.345 | 2 / 1 | 3.2 | Yes |
| 13659 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 17942 |  CHEMBL75257 | C16H23N3O | 273.38 | 3 / 2 | 4.3 | Yes |
| 18663 |  CHEMBL286246 | C11H10N2S | 202.275 | 2 / 1 | 2.1 | Yes |
| 19607 |  CHEMBL327116 | C15H19N3O2S | 305.396 | 4 / 2 | 2.1 | Yes |
| 21394 |  CHEMBL77913 | C11H13N3O | 203.245 | 3 / 2 | 2.3 | Yes |
| 21603 |  CHEMBL543964 | C16H16ClN3O | 301.774 | 1 / 3 | N/A | N/A |
| 22605 |  CHEMBL284213 | C11H12N2S | 204.291 | 2 / 1 | 2.3 | Yes |
| 26601 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 32033 |  CHEMBL88160 | C26H34F3N7O2 | 533.6 | 10 / 1 | 4.3 | No |
| 39244 |  CHEMBL74449 | C11H9N5 | 211.228 | 4 / 2 | 1.2 | Yes |
| 43161 |  64022-27-1 | C8H11ClN4 | 198.654 | 4 / 1 | 0.5 | Yes |
| 49860 |  CHEMBL304132 | C32H36N4O4 | 540.664 | 6 / 1 | 4.9 | No |
| 50974 |  SCHEMBL9697598 | C14H15N3 | 225.295 | 1 / 1 | 2.0 | Yes |
| 63180 |  phenylpropanolamine | C9H13NO | 151.209 | 2 / 2 | 0.8 | Yes |
| 66966 |  TAMSULOSIN | C20H28N2O5S | 408.513 | 7 / 2 | 2.7 | Yes |
| 70965 |  CHEMBL111496 | C15H19N3O2S | 305.396 | 4 / 2 | 2.1 | Yes |
| 73288 |  Pentiapine | C15H17N5S | 299.396 | 4 / 0 | 3.5 | Yes |
| 80173 |  CHEMBL1019 | C11H8BrN5 | 290.124 | 4 / 2 | 1.9 | Yes |
| 83875 |  Ketanserin | C22H22FN3O3 | 395.434 | 5 / 1 | 2.6 | Yes |
| 87190 |  CHEMBL111554 | C14H17N3O2S | 291.369 | 4 / 2 | 1.7 | Yes |
| 88068 |  CHEMBL111463 | C15H19N3O2S | 305.396 | 4 / 1 | 1.9 | Yes |
| 98232 |  clonidine | C9H9Cl2N3 | 230.092 | 1 / 2 | 1.6 | Yes |
| 103734 |  akuammigine | C21H24N2O3 | 352.434 | 4 / 1 | 2.7 | Yes |
| 103740 |  .delta.-Yohimbine | C21H24N2O3 | 352.434 | 4 / 1 | 2.7 | Yes |
| 105683 |  CHEMBL90746 | C27H33N5O | 443.595 | 5 / 1 | 4.8 | Yes |
| 115541 |  7-Hydroxychlorpromazine | C17H19ClN2OS | 334.862 | 4 / 1 | 4.8 | Yes |
| 118232 |  CHEMBL131220 | C12H13FN2 | 204.248 | 2 / 1 | 1.6 | Yes |
| 118315 |  A-119637 | C25H26N4O3S | 462.568 | 6 / 1 | 3.9 | Yes |
| 120825 |  IDAZOXAN | C11H12N2O2 | 204.229 | 3 / 1 | 0.7 | Yes |
| 121139 |  1-(3-fluoropyridin-2-yl)piperazine | C9H12FN3 | 181.214 | 4 / 1 | 0.8 | Yes |
| 123182 |  Atipamezole | C14H16N2 | 212.296 | 1 / 1 | 3.0 | Yes |
| 128192 |  RS-102221 | C27H31F3N4O7S | 612.621 | 12 / 3 | 2.7 | No |
| 131208 |  apraclonidine | C9H10Cl2N4 | 245.107 | 2 / 3 | 1.3 | Yes |
| 131369 |  prazosin | C19H21N5O4 | 383.408 | 8 / 1 | 2.0 | Yes |
| 139588 |  CHEMBL431362 | C32H36N4O5 | 556.663 | 7 / 2 | 3.9 | No |
| 146677 |  RS 67333 | C19H29ClN2O2 | 352.903 | 4 / 1 | 3.8 | Yes |
| 148123 |  CHEMBL432155 | C12H14N4O | 230.271 | 4 / 3 | 2.0 | Yes |
| 152004 |  tolazoline | C10H12N2 | 160.22 | 1 / 1 | 2.6 | Yes |
| 154445 |  CHEMBL1022 | C9H7Cl2N3 | 228.076 | 2 / 2 | 3.2 | Yes |
| 157919 |  MK-912 | C20H25N3O2 | 339.439 | 3 / 0 | 2.3 | Yes |
| 160839 |  Spiroxatrine | C22H25N3O3 | 379.46 | 5 / 1 | 3.1 | Yes |
| 161311 |  CHEMBL338683 | C12H12Cl2N2 | 255.142 | 1 / 1 | 2.7 | Yes |
| 169259 |  CHEMBL76457 | C9H8BrN3 | 238.088 | 2 / 2 | 2.6 | Yes |
| 171809 |  thioridazine | C21H26N2S2 | 370.573 | 4 / 0 | 5.9 | No |
| 189092 |  Wy 26392 | C17H26N2O2S | 322.467 | 4 / 0 | 2.6 | Yes |
| 194143 |  CHEMBL309106 | C33H39N5O5 | 585.705 | 8 / 2 | 3.6 | No |
| 194468 |  A 61603 HYDROBROMIDE | C14H20BrN3O3S | 390.296 | 5 / 4 | N/A | N/A |
| 197338 |  AC1L33GU | C18H28N2O2S | 336.494 | 4 / 0 | 2.9 | Yes |
| 199416 |  Piperoxan | C14H19NO2 | 233.311 | 3 / 0 | 2.6 | Yes |
| 201797 |  SK&F-104078 | C16H22ClNO | 279.808 | 2 / 0 | 4.4 | Yes |
| 212187 |  AC1NKXXY | C17H19N3O | 281.359 | 2 / 2 | 3.3 | Yes |
| 215594 |  CHEMBL304591 | C32H36N4O5 | 556.663 | 7 / 1 | 4.5 | No |
| 220504 |  AGN 192836 | C12H13N3O2 | 231.255 | 4 / 2 | 2.0 | Yes |
| 222219 |  CHEMBL74544 | C10H9N5 | 199.217 | 3 / 3 | 1.5 | Yes |
| 230088 |  CHEMBL98471 | C13H16N2 | 200.285 | 1 / 1 | 1.8 | Yes |
| 230785 |  76537-53-6 | C10H13N5 | 203.249 | 4 / 1 | 0.5 | Yes |
| 231083 |  CHEMBL41720 | C12H14FN3 | 219.263 | 3 / 1 | 1.2 | Yes |
| 234976 |  Azapetine | C17H17N | 235.33 | 1 / 0 | 3.6 | Yes |
| 236764 |  CHEMBL133231 | C12H13ClN2O | 236.699 | 2 / 1 | 2.1 | Yes |
| 243297 |  143797-63-1 | C15H14N4O | 266.304 | 2 / 2 | 1.5 | Yes |
| 244517 |  A-131701 | C24H24N4O3S | 448.541 | 6 / 1 | 3.2 | Yes |
| 245833 |  CHEMBL420620 | C22H30FN5O2 | 415.513 | 7 / 1 | 3.2 | Yes |
| 247715 |  A61603 | C14H19N3O3S | 309.384 | 5 / 3 | 0.4 | Yes |
| 249107 |  D0V8NS | C25H30N2O3 | 406.526 | 5 / 0 | 4.2 | Yes |
| 249280 |  AGN-193080 | C12H16N4O | 232.287 | 3 / 3 | 0.7 | Yes |
| 253357 |  4-Chloro-2-(2-imidazolin-2-ylamino)isoindoline | C11H13ClN4 | 236.703 | 2 / 2 | 1.0 | Yes |
| 254924 |  A-123189 | C26H28N4O3S | 476.595 | 6 / 1 | 4.2 | Yes |
| 256418 |  CHEMBL133579 | C13H16N2O | 216.284 | 2 / 1 | 1.4 | Yes |
| 259276 |  AGN-192172 | C12H17N5 | 231.303 | 3 / 4 | 0.7 | Yes |
| 260878 |  CHEMBL111771 | C14H17N3O2S | 291.369 | 4 / 2 | 1.5 | Yes |
| 262520 |  FLUPHENAZINE | C22H26F3N3OS | 437.525 | 8 / 1 | 4.4 | Yes |
| 271641 |  Ethoxyidazoxan | C13H16N2O3 | 248.282 | 4 / 1 | 0.8 | Yes |
| 273154 |  HEAT | C19H21NO2 | 295.382 | 3 / 2 | 3.8 | Yes |
| 276265 |  CHEMBL78190 | C15H21N3O | 259.353 | 3 / 2 | 3.9 | Yes |
| 285305 |  CHEMBL30534 | C11H8N2S | 200.259 | 2 / 1 | 2.7 | Yes |
| 290836 |  CHEMBL49137 | C12H13N5 | 227.271 | 3 / 2 | 0.3 | Yes |
| 292024 |  Setoperone | C21H24FN3O2S | 401.5 | 6 / 0 | 2.8 | Yes |
| 292641 |  CHEMBL89030 | C24H34N4O2 | 410.562 | 5 / 1 | 4.2 | Yes |
| 299095 |  CHEMBL284795 | C13H14N2S | 230.329 | 2 / 1 | 2.8 | Yes |
| 300028 |  CHEMBL108804 | C14H17N3O3S | 307.368 | 5 / 3 | 1.4 | Yes |
| 300691 |  CHEMBL524153 | C28H32N4O4 | 488.588 | 7 / 1 | 3.7 | Yes |
| 301539 |  ABT-866 | C12H15N3O2S | 265.331 | 4 / 2 | 1.4 | Yes |
| 304113 |  benalfocin | C11H14ClN | 195.69 | 1 / 0 | 2.9 | Yes |
| 310831 |  CHEMBL6310 | C12H14N2O | 202.257 | 2 / 2 | 1.5 | Yes |
| 312972 |  norepinephrine | C8H11NO3 | 169.18 | 4 / 4 | -1.2 | Yes |
| 314759 |  CHEMBL430112 | C10H19N | 153.269 | 1 / 1 | 2.3 | Yes |
| 317058 |  CHEMBL130853 | C12H14N2 | 186.258 | 1 / 1 | 1.5 | Yes |
| 325761 |  CHEMBL109848 | C15H17N3O | 255.321 | 2 / 2 | 1.9 | Yes |
| 328682 |  fenoldopam | C16H16ClNO3 | 305.758 | 4 / 4 | 2.4 | Yes |
| 332171 |  RS-67506 | C18H28ClN3O4S | 417.949 | 7 / 2 | 1.7 | Yes |
| 334988 |  (S)-mianserin | C18H20N2 | 264.372 | 2 / 0 | 3.4 | Yes |
| 335442 |  CHEMBL346389 | C19H20ClN3O2 | 357.838 | 4 / 1 | 2.9 | Yes |
| 343633 |  CHEMBL317912 | C13H14N2O | 214.268 | 2 / 2 | 2.4 | Yes |
| 346460 |  SCHEMBL8097715 | C25H27NO5 | 421.493 | 6 / 1 | 4.4 | Yes |
| 555016 |  Imiloxan | C14H16N2O2 | 244.294 | 3 / 0 | 2.1 | Yes |
| 351666 |  terazosin | C19H25N5O4 | 387.44 | 8 / 1 | 1.4 | Yes |
| 353952 |  3600-87-1 | C10H15NO3 | 197.234 | 4 / 2 | 0.1 | Yes |
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