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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	TAMSULOSIN
Molecular formula	C20H28N2O5S
IUPAC name	5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
Molecular weight	408.513
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	2.7
Synonyms	Tamsulosinum 814-EP2298767A1 ACT02653 AX8041134 Contiflo OD DTXSID3023631 G3P28OML5I LS-31578 (-)-YM617 SCHEMBL34378 133T204 Tamsulon (TN) 5-[(2S)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide Urimax (TN) A801388 AKOS005266643 BIDD:GT0261 D05MBZ Flomax (TN) HMS2090P15 NCGC00167442-01 (R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide SR-05000001519-1 5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide Tamsulosin [INN:BAN] Tamsulosine 814-EP2295426A1 AB1008589 ANW-58646 DB00706 FT-0082894 KB-210214 Q-101875 (r)-tamsulosin Tamsolusin 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonamide Tamsulosinum [INN-Latin] 814-EP2305254A1 AJ-26680 BDBM50060964 CS-2896 EBD36303 GTPL488 MLS006011810 (r)-(-)-tamsulosin SMR004703489 5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide 814-EP2269989A1 YM-617 A835382 Amsulosin C07124 D08560 Flomaxtra (TN) HSDB 7744 NCGC00167442-02 (r)-5-(2-(2-(2-ethoxyphenoxy)ethylamino)propyl)-2-methoxybenzenesulfonamide ST24035500 5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide Tamsulosina Tamsulosine [INN-French] 814-EP2295427A1 AC1L2V76 API0010078 CHEMBL836 DRHKJLXJIQTDTD-OAHLLOKOSA-N FT-0601581 KS-00000L19 (-)-Tamsulosin RT-024223 106133-20-4 Tamsulon 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide UNII-G3P28OML5I 814-EP2314587A1 AK-78696 Benzenesulfonamide, 5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxy-, (R)- CTK8B7795 Flomax Harnal-D MolPort-003-850-388 (R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)-propyl)-2-methoxybenzenesulfonamide SR-05000001519 5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide Tamsulosin (INN) 5-{(2R)-2-[(2-{[2-(ethyloxy)phenyl]oxy}ethyl)amino]propyl}-2-(methyloxy)benzenesulfonamide 814-EP2270011A1 ZINC1530694 AB01275521-01 AN-10808 CHEBI:9398 Flowmax HY-B0661 PubChem21320 (r)-5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-benzenesulfonamide STK626950 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzene-sulfonamide Tamsulosina [INN-Spanish] [ Show all ]
Inchi Key	DRHKJLXJIQTDTD-OAHLLOKOSA-N
Inchi ID	InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1
PubChem CID	129211
ChEMBL	CHEMBL836
IUPHAR	488
BindingDB	50060964
DrugBank	DB00706
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
66955	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
66964	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
66954	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
66962	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
66963	Alpha-1A adrenergic receptor	O02824	ADRA1A	Oryctolagus cuniculus (Rabbit)	466
66965	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
66953	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
66959	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
66968	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
66956	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
66957	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
66950	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
66960	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
66966	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
66952	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
66958	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
66951	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
66967	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
66961	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488

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