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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1L33GU
Molecular formula	C18H28N2O2S
IUPAC name	N-[(2S,11bR)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]-N-methylbutane-1-sulfonamide
Molecular weight	336.494
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.9
Synonyms	WY26703 BDBM81816 N-[(2S,11bR)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]-N-methylbutane-1-sulfonamide hydrochloride AC1L33GX CAS_82059-49-2 PDSP2_001640 AR-1K2981 N-[(2S,11bR)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]-N-methylbutane-1-sulfonamide [ Show all ]
Inchi Key	LVHNKZNYJNTKDF-FUHWJXTLSA-N
Inchi ID	InChI=1S/C18H28N2O2S/c1-3-4-13-23(21,22)19(2)16-10-12-20-11-9-15-7-5-6-8-17(15)18(20)14-16/h5-8,16,18H,3-4,9-14H2,1-2H3/t16-,18+/m0/s1
PubChem CID	133820
ChEMBL	N/A
IUPHAR	N/A
BindingDB	81816
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
197337	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
197338	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453

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