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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	143797-63-1
Molecular formula	C15H14N4O
IUPAC name	1-(1-methylindol-5-yl)-3-pyridin-3-ylurea
Molecular weight	266.304
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	1.5
Synonyms	AC1L2QVR DTXSID40162550 PDSP1_001636 SB200646a BRD-K77677632-003-01-8 N-(1-Methyl-1H-indol-5-yl)-N'-3-pyridinylurea SB 200646 HCl Urea, N-(1-methyl-1H-indol-5-yl)-N'-3-pyridinyl- 1-(1-Methyl-1H-indol-5-yl)-3-(pyridin-3-yl)urea NCGC00025128-01 SB-200646 hydrochloride AKOS027422836 L000535 PDSP2_001620 SCHEMBL173735 C11739 N-(1-methyl-5-indolyl)-N'-(3-pyridyl) urea SB 200646A ZINC5475 1-(1-methylindol-5-yl)-3-(3-pyridyl)urea CHEMBL85194 NCGC00025128-02 SB200646 BDBM82272 Mip-urea SB 200646 Tocris-1371 1-(1-methylindol-5-yl)-3-pyridin-3-ylurea CHEBI:8976 N-(1-Methyl-5-indolyl)-N'-(3-pyridyl)urea SB-200646 [ Show all ]
Inchi Key	OJZZJTLBYXHUSJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H14N4O/c1-19-8-6-11-9-12(4-5-14(11)19)17-15(20)18-13-3-2-7-16-10-13/h2-10H,1H3,(H2,17,18,20)
PubChem CID	126769
ChEMBL	CHEMBL85194
IUPHAR	N/A
BindingDB	82272
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
243294	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
243291	5-hydroxytryptamine receptor 1D	Q60484	HTR1D	Cavia porcellus (Guinea pig)	376
243290	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
243293	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
243288	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
243296	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
243285	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
243286	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
243289	5-hydroxytryptamine receptor 2C	P34968	Htr2c	Mus musculus (Mouse)	459
243295	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
243298	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
243297	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
243287	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
461311	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
243292	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
556422	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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