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GLASS

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	5-hydroxytryptamine receptor 2C
Species	Mus musculus (Mouse)
Gene	Htr2c
Synonym	5-HT-1C serotonin 1c receptor HTR1C 5-hydroxytryptamine receptor 1C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 5-HTR2C 5-HT2C receptor 5-HT2C 5-HT1C 5-HT-2C Serotonin receptor 2C [ Show all ]
Disease	N/A for non-human GPCRs
Length	459
Amino acid sequence	MVNLGTAVRSLLVHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELRNISLNFLKCCCKKGDEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVVRKANDTEPGIEMQVENLELPVNPSNVVSERISSV
UniProt	P34968
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3006
IUPHAR	N/A
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
20175	imipramine	C19H24N2	280.415	2 / 0	4.8	Yes
23176	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine	C11H16INO2	321.158	3 / 1	2.5	Yes
26605	Yohimbine	C21H26N2O3	354.45	4 / 2	2.9	Yes
94366	CHEMBL47482	C15H15N	209.292	1 / 1	2.7	Yes
128200	RS-102221	C27H31F3N4O7S	612.621	12 / 3	2.7	No
152222	CYPROHEPTADINE	C21H21N	287.406	1 / 0	4.7	Yes
199761	159277-08-4	C11H14F3NO2	249.233	6 / 1	2.1	Yes
243289	143797-63-1	C15H14N4O	266.304	2 / 2	1.5	Yes
543332	CHEMBL3946540	C21H25ClN2O2	372.893	4 / 0	4.1	Yes
279939	SB 206553	C17H16N4O	292.342	2 / 1	1.7	Yes
544117	CHEMBL3986651	C22H28N2O3	368.477	5 / 0	3.4	Yes
544229	CHEMBL3942898	C21H25FN2O2	356.441	5 / 0	3.6	Yes
344292	SB 204741	C14H14N4OS	286.353	3 / 2	2.4	Yes
379001	Racemic DOTFM	C12H16F3NO2	263.26	6 / 1	2.8	Yes
553112	CHEMBL3963147	C22H27N3O3	381.476	5 / 0	2.8	Yes
570600	SCHEMBL15746102	C22H27N3O3	381.476	5 / 0	2.8	Yes
547585	CHEMBL3946661	C21H26N2O2	338.451	4 / 0	3.5	Yes

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