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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3946661
Molecular formula	C21H26N2O2
IUPAC name	(2S)-4-[2-(2,3-dihydroindol-1-yl)ethyl]-2-(phenoxymethyl)morpholine
Molecular weight	338.451
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.5
Synonyms	US9079895, 19s ZKTUDHGKQCWRDH-FQEVSTJZSA-N BDBM186927 SCHEMBL14061666 (S)-4-(2-(Indolin-1-yl)ethyl)-2-(phenoxymethyl)morpholine
Inchi Key	ZKTUDHGKQCWRDH-FQEVSTJZSA-N
Inchi ID	InChI=1S/C21H26N2O2/c1-2-7-19(8-3-1)25-17-20-16-22(14-15-24-20)12-13-23-11-10-18-6-4-5-9-21(18)23/h1-9,20H,10-17H2/t20-/m0/s1
PubChem CID	71062646
ChEMBL	CHEMBL3946661
IUPHAR	N/A
BindingDB	186927
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
547591	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
547589	5-hydroxytryptamine receptor 1D	Q61224	Htr1d	Mus musculus (Mouse)	374
547583	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
547581	5-hydroxytryptamine receptor 2B	Q02152	Htr2b	Mus musculus (Mouse)	479
547585	5-hydroxytryptamine receptor 2C	P34968	Htr2c	Mus musculus (Mouse)	459
547586	5-hydroxytryptamine receptor 7	P32304	Htr7	Mus musculus (Mouse)	448
547587	Alpha-1A adrenergic receptor	P97718	Adra1a	Mus musculus (Mouse)	466
547584	Alpha-1B adrenergic receptor	P97717	Adra1b	Mus musculus (Mouse)	514
547588	Alpha-1D adrenergic receptor	P97714	Adra1d	Mus musculus (Mouse)	562
547590	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
547592	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444
547593	D(3) dopamine receptor	P30728	Drd3	Mus musculus (Mouse)	446
547582	D(4) dopamine receptor	P51436	Drd4	Mus musculus (Mouse)	387

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