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You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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GPCR

Name	5-hydroxytryptamine receptor 2A
Species	Mus musculus (Mouse)
Gene	Htr2a
Synonym	serotonin 5HT-2 receptor 5Ht-2 'D' receptor 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 5-HT2A receptor 5-HT-2A 5-HT-2 Serotonin receptor 2A [ Show all ]
Disease	N/A for non-human GPCRs
Length	471
Amino acid sequence	MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYKSSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
UniProt	P35363
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5377
IUPHAR	N/A
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
1345	SR-01000300690	C22H22N4O3	390.443	4 / 2	2.5	Yes
3227	MLS000859925	C34H41N5O8S	679.789	9 / 4	N/A	No
3231	Dihydroergotamine mesylate	C34H41N5O8S	679.789	9 / 4	N/A	No
3411	MLS001217465	C23H24N2O7	440.452	8 / 2	N/A	N/A
3557	MLS000735483	C22H28ClNO	357.922	2 / 1	5.1	No
4341	talipexole hydrochloride	C10H16ClN3S	245.769	4 / 2	N/A	N/A
8742	SR-01000835302	C25H26ClN3O3S	484.011	5 / 0	4.0	Yes
536268	CHEMBL3915107	C21H23ClN2O3	386.876	4 / 0	3.4	Yes
557600	SCHEMBL14060375	C21H23ClN2O3	386.876	4 / 0	3.4	Yes
12316	MLS001150220	C16H18N4O3	314.345	7 / 1	1.4	Yes
13624	ADTN	C10H13NO2	179.219	3 / 3	1.4	Yes
13675	8-OH-Dpat	C16H25NO	247.382	2 / 1	4.1	Yes
13765	(+/-)-Epinephrine hydrochloride	C9H14ClNO3	219.665	4 / 4	N/A	N/A
14824	MLS000092499	C26H31FN4O2S	482.618	6 / 1	3.5	Yes
18401	SMR000060792	C23H31N3O5S	461.577	8 / 1	1.7	Yes
19165	CID 44711860	C16H26BrNO	328.294	2 / 2	N/A	N/A
23170	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine	C11H16INO2	321.158	3 / 1	2.5	Yes
24809	lysergol	C16H18N2O	254.333	2 / 2	2.2	Yes
25003	AC1MRYRM	C17H20ClN3O3S2	413.935	6 / 2	2.2	Yes
27246	MLS001076459	C20H24N4O3	368.437	4 / 0	2.5	Yes
27820	MLS002222327	C23H28ClN3O7	493.941	9 / 4	N/A	N/A
28816	AC1MF4HX	C25H33N3O7S	519.613	10 / 2	N/A	No
28968	4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-6-nitro-quinazoline	C20H20ClN5O4	429.861	8 / 1	N/A	N/A
29290	4-bromo-2-methoxy-6-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]phenol	C16H19BrN4O2	379.258	6 / 1	2.3	Yes
29467	AC1MCIX6	C19H15ClN6O3S2	474.938	8 / 3	3.7	Yes
30393	Dobutamine hydrochloride	C18H24ClNO3	337.844	4 / 5	N/A	N/A
34459	A 77636 hydrochloride	C20H28ClNO3	365.898	4 / 4	N/A	N/A
36705	N-(4-ethoxyphenyl)-3-[4-(2-fluorophenyl)piperazin-1-yl]propanamide	C21H26FN3O2	371.456	5 / 1	3.1	Yes
39336	MLS000105277	C17H22N4O2	314.389	6 / 0	1.9	Yes
39882	BRN 0563047	C17H19N3O2	297.358	5 / 0	2.4	Yes
40306	Aripiprazole	C23H27Cl2N3O2	448.388	4 / 1	4.6	Yes
42169	ethisterone	C21H28O2	312.453	2 / 1	3.5	Yes
42605	MLS000117927	C21H29FN6O3S	464.56	8 / 2	1.0	Yes
45489	[4-(4-Fluoro-benzyl)-piperazin-1-yl]-furan-2-yl-methanone	C18H19FN2O6	378.356	8 / 2	N/A	N/A
49949	R(+)-6-Bromo-APB hydrobromide	C19H21Br2NO2	455.19	3 / 3	N/A	N/A
51559	FENOLDOPAM MESYLATE	C17H20ClNO6S	401.858	7 / 5	N/A	N/A
54517	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-4-phenylpiperazine	C14H16ClN3S	293.813	4 / 0	3.4	Yes
54887	MLS000735390	C19H25ClN2O2	348.871	3 / 0	2.8	Yes
56297	(+)-PD 128907 hydrochloride	C14H20ClNO3	285.768	4 / 2	N/A	N/A
56424	MLS000734475	C22H30ClN3O2	403.951	4 / 0	4.1	Yes
57066	SMR000102164	C15H17FN4	272.327	5 / 0	2.1	Yes
58293	Piribedil mesylate	C17H22N4O5S	394.446	9 / 1	N/A	N/A
59752	MLS000106452	C17H24FN3O	305.397	4 / 0	2.0	Yes
60309	Talipexole	C10H15N3S	209.311	4 / 1	1.5	Yes
61274	MLS001090560	C22H25N3O5	411.458	7 / 0	2.5	Yes
537595	CHEMBL3936182	C21H27N3O2	353.466	5 / 0	2.8	Yes
559350	SCHEMBL14149621	C21H27N3O2	353.466	5 / 0	2.8	Yes
66434	2-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]pyrimidine	C15H17ClN4	288.779	4 / 0	2.6	Yes
66531	MLS000069811	C17H20ClNO3	321.801	4 / 4	N/A	N/A
66823	SMR000082072	C24H29N7O	431.544	8 / 1	3.5	Yes
71898	SMR000236404	C19H25Cl2N3O2	398.328	5 / 2	N/A	N/A
72160	3-(2-Methylaminoethyl)indol-5-ol oxalate	C13H16N2O5	280.28	6 / 5	N/A	N/A
77678	1-Benzyl-1,2,3,6-tetrahydro-pyridine-4-carboxylic acid ethyl ester	C15H20ClNO2	281.78	3 / 1	N/A	N/A
80723	MLS001060812	C11H14ClNO2	227.688	3 / 4	N/A	N/A
82441	SMR000060793	C23H31N3O6S	477.576	9 / 2	1.3	Yes
83732	MLS000711510	C20H24N2O8	420.418	9 / 2	N/A	N/A
84432	MLS000696689	C19H18N4O3S	382.438	7 / 1	2.2	Yes
84536	SMR000026289	C25H31FN4O3S	486.606	7 / 1	3.0	Yes
86554	riluzole	C8H5F3N2OS	234.196	7 / 1	3.6	Yes
89800	SMR000146505	C19H24ClFN2O3	382.86	5 / 1	N/A	N/A
90303	AKOS003669690	C20H26ClN3O2	375.897	4 / 2	N/A	N/A
90912	AC1N9R7M	C22H31N5O3S	445.582	7 / 1	2.3	Yes
93240	2-methoxy-N-[2-(4-phenylpiperazin-1-yl)ethyl]benzamide	C20H25N3O2	339.439	4 / 1	2.6	Yes
95180	SMR000354270	C30H34N4O2	482.628	4 / 0	6.1	No
96797	SR-01000181557	C22H35N3O4	405.539	6 / 1	2.0	Yes
96949	MLS000773968	C20H19NO3S	353.436	4 / 3	4.3	Yes
97948	MLS001183932	C17H18Cl2N4O4	413.255	8 / 2	N/A	N/A
560355	MLS001165031	C20H21N3O2	335.407	5 / 2	4.4	Yes
98725	CGP 20712A	C23H25F3N4O5	494.471	10 / 4	2.3	Yes
98743	3-{[4-(pyrimidin-2-yl)piperazin-1-yl]methyl}-1h-indole	C17H19N5	293.374	4 / 1	2.0	Yes
102529	MLS003315743	C26H30N6O2	458.566	7 / 0	3.5	Yes
108477	MLS000759653	C21H26N4O8S	494.519	11 / 4	N/A	No
109626	MLS003389489	C13H20ClNO3	273.757	4 / 3	N/A	N/A
112886	1-(ethylsulfonyl)-N-{3-[4-(2-fluorophenyl)piperazin-1-yl]propyl}piperidine-4-carboxamide	C21H33FN4O3S	440.578	7 / 1	1.7	Yes
113733	SMR000060790	C23H30ClN3O5S	496.019	8 / 1	2.3	Yes
114615	GNF-Pf-3343	C21H27ClN4OS	418.984	4 / 1	5.3	No
116387	(-)-Quinpirole hydrochloride	C13H22ClN3	255.79	2 / 2	N/A	N/A
549369	CHEMBL3986799	C22H29N3O2	367.493	5 / 0	3.2	Yes
561056	SCHEMBL14060090	C22H29N3O2	367.493	5 / 0	3.2	Yes
122465	1-Benzo[1,3]dioxol-5-ylmethyl-4-(3-nitro-pyridin-2-yl)-piperazine	C17H19ClN4O4	378.813	7 / 1	N/A	N/A
123846	UNII-8L7H229K4I	C14H21NO	219.328	2 / 1	3.0	Yes
130640	2-{4-[4-(Furan-2-carbonyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione	C21H23N3O4	381.432	5 / 0	2.0	Yes
132360	SR-01000201524	C18H24N4O	312.417	5 / 0	2.7	Yes
134087	SMR000064143	C24H27NO7	441.48	8 / 3	N/A	N/A
135719	MLS000059215	C23H25N3O	359.473	4 / 0	4.1	Yes
139230	AC1NU6H5	C20H16N2O2	316.36	4 / 0	4.9	Yes
139900	SMR000033389	C23H24N4O2	388.471	5 / 1	3.6	Yes
140351	3-{2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-2-oxoethyl}-4(3H)-quinazolinone	C22H22N4O4	406.442	6 / 0	1.5	Yes
141151	MLS000681264	C26H29N3O2	415.537	4 / 1	4.5	Yes
142790	AC1PCYHY	C17H22N2O5	334.372	6 / 1	1.2	Yes
144519	MLS000093376	C19H29N3O3	347.459	4 / 2	2.2	Yes
146283	MLS000108391	C19H24N2O4	344.411	5 / 0	2.4	Yes
146963	SMR000047376	C19H21ClN8	396.883	8 / 2	2.9	Yes
147318	N-Methyldopamine hydrochloride	C9H14ClNO2	203.666	3 / 4	N/A	N/A
148112	methyl 1-[3-(4-{[4-(4-nitrophenyl)piperazino]methyl}phenoxy)propyl]-4-piperidinecarboxylate	C27H36N4O5	496.608	8 / 0	3.9	Yes
152768	SR-01000201826	C14H17N3S	259.371	4 / 0	2.3	Yes
155675	terguride	C20H28N4O	340.471	2 / 2	2.5	Yes
158238	SR-01000446204	C19H25N3O3	343.427	6 / 1	2.1	Yes
158492	dobutamine	C18H23NO3	301.386	4 / 4	3.4	Yes
159088	MLS000674842	C19H24Cl2N2O	367.314	2 / 0	4.0	Yes

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