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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 2A
Species	Mus musculus (Mouse)
Gene	Htr2a
Synonym	serotonin 5HT-2 receptor 5Ht-2 'D' receptor 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 5-HT2A receptor 5-HT-2A 5-HT-2 Serotonin receptor 2A [ Show all ]
Disease	N/A for non-human GPCRs
Length	471
Amino acid sequence	MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYKSSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
UniProt	P35363
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5377
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	3-(2-Methylaminoethyl)indol-5-ol oxalate
Molecular formula	C13H16N2O5
IUPAC name	3-[2-(methylamino)ethyl]-1H-indol-5-ol;oxalic acid
Molecular weight	280.28
Hydrogen bond acceptor	6
Hydrogen bond donor	5
XlogP	None
Synonyms	HMS3262E08 N-Methylserotonin oxalate Nomega-Methyl-5-hydroxy??trypt??amine oxalate salt, >=98% (alkalimetric) SR-01000075980 1975-81-1 5-hydroxy-nw-methyltryptamine oxalate CHEMBL1256286 LP00743 N-omega-Methylserotonin NSC91541 Tox21_500743 3-[2-(methylamino)ethyl]-1H-indol-5-ol; oxalic acid AC1Q5RMG EINECS 239-611-4 MFCD00013159 Nomega'-Methyl-5-hydroxy trypt amine oxalate salt SCHEMBL1320479 5-Hydroxy-Nomega-methyltryptamine oxalate CCG-222047 H-7000 HMS3371J12 N-omega-METHYL-5-HYDROXYTRYPTAMINE Nomega-Methylserotonin oxalate salt SR-01000075980-1 3-(2-(Methylamino)ethyl)-1H-indol-5-ol oxalate 5-Hydroxy-N\|O-methyltryptamine oxalate CTK0I2793 M 1514 NCGC00094085-01 N\|O-Methyl-5-hydroxy-trypt-amine oxalate salt 3-[2-(methylamino)ethyl]indol-5-ol, ethanedioic acid ACM1975811 EU-0100743 MLS000859941 Nomega-Methyl-5-hydroxy-trypt-amine oxalate salt SMR000326801 15558-50-6 5-Hydroxy-Nomega-methyltryptamine oxalate, 99% HMS2234N19 J-012764 N-omega-Methyl-5-hydroxytryptamine oxalate salt NSC-91541 ST055634 AC1L6327 DTXSID80293695 MCULE-1823155663 NCGC00261428-01 N\|O-Methylserotonin oxalate salt 5-Hydroxy-N-omega-methyltryptamine, oxalate salt AKOS024282337 FT-0620492 [ Show all ]
Inchi Key	DYOZWAJOUTVNAF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H14N2O.C2H2O4/c1-12-5-4-8-7-13-11-3-2-9(14)6-10(8)11;3-1(4)2(5)6/h2-3,6-7,12-14H,4-5H2,1H3;(H,3,4)(H,5,6)
PubChem CID	260390
ChEMBL	CHEMBL1256286
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
EC50	1729.0 nM	PubChem BioAssay data set	ChEMBL

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