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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	dobutamine
Molecular formula	C18H23NO3
IUPAC name	4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol
Molecular weight	301.386
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	3.4
Synonyms	34368-04-2 rac-dobutamine 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol(Dobutamine) AKOS025248013 CAS-34368-04-2 D0J7RK Dobutamine (USP/INN) Dobutaminum GTPL535 MCULE-6655494898 NCGC00015321-09 NCGC00024629-03 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol SPBio_002364 BDBM50325274 DL-dobutamine Dobutamine Tartrate (1:1), (S-(R,R))-Isomer DSSTox_CID_2958 L001157 NCGC00015321-04 (.+/-.)-4-[2-[[3-(p-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]pyrocatechol 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride Prestwick2_000352 4-[2-[[3-(4-hydroxyphenyl)-1-methyl-propyl]amino]ethyl]benzene-1,2-diol Tox21_110126 AC1L1WFF BSPBio_000443 Compound 81929 Dobutamina [INN-Spanish] Dobutamine [USAN] DTXSID3022958 LS-174467 NCGC00015321-07 4-(2-([3-(4-Hydroxyphenyl)-1-methylpropyl]amino)ethyl)-1,2-benzenediol # racemic-Dobutamine API0014455 CCG-204460 Dobutamine Hcl in Dextrose 5% Dobutaminum [INN-Latin] HMS2089K05 MolPort-006-167-641 (+-)-4-(2-((3-(p-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol NCGC00015321-11 Prestwick0_000352 4-[2-[3-(4-Hydroxyphenyl)-1-methylpropylamino]ethyl]pyrocatechol SR-01000075265-9 67230-43-7 BPBio1_000489 CHEMBL926 Dobutamin Dobutamine [USAN:BAN:INN] DSSTox_GSID_22958 Lilly 81929 NCGC00015321-05 1,2-Benzenediol, 4-(2-((3-(4-hydroxyphenyl)-1-methylpropyl)amino)ethyl)-, (+-)- 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine Prestwick3_000352 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol Tox21_110126_1 AC1Q7AD1 C06967 D03879 dobutamine(usp) FT-0625556 LY 81929 NCGC00015321-08 NCGC00024629-02 4-(2-{[3-(4-hydroxyphenyl)-1-methylpropyl]amino}ethyl)benzene-1,2-diol SCHEMBL21237 52663-81-7 (hydrochloride) BBL033719 CHEBI:4670 DB00841 Dobutamine hydrobromide Dobutrex JRWZLRBJNMZMFE-UHFFFAOYSA-N NCGC00015321-03 (-)-Dobutamine Prestwick1_000352 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol STL373008 74753-15-4 (hydrobromide) BRD-A78322124-003-03-3 cid_36811 Dobutamina Dobutamine [USAN:USP:INN:BAN] DSSTox_RID_76807 Lopac0_000365 NCGC00015321-06 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, (.+/-.)- [ Show all ]
Inchi Key	JRWZLRBJNMZMFE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H23NO3/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15/h4-9,12-13,19-22H,2-3,10-11H2,1H3
PubChem CID	36811
ChEMBL	CHEMBL926
IUPHAR	535
BindingDB	50325274
DrugBank	DB00841
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
158492	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
447941	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
158489	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
158484	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
158488	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
158483	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
158486	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
158491	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
158487	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
158490	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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