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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-4-phenylpiperazine
Molecular formula	C14H16ClN3S
IUPAC name	2-chloro-5-[(4-phenylpiperazin-1-yl)methyl]-1,3-thiazole
Molecular weight	293.813
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.4
Synonyms	478248-87-2 HMS2672M18 AKOS015993799 MLS000721352 CHEMBL1487540 SMR000335424 9P-927 KS-00003GFA Bionet2_000634 MolPort-002-883-444 2-chloro-5-[(4-phenylpiperazin-1-yl)methyl]-1,3-thiazole HMS1365M18 ZINC20405793 AC1LSJS0 MCULE-9283624051 Oprea1_559185 [ Show all ]
Inchi Key	CZPHEYMHFHOUKP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H16ClN3S/c15-14-16-10-13(19-14)11-17-6-8-18(9-7-17)12-4-2-1-3-5-12/h1-5,10H,6-9,11H2
PubChem CID	1489112
ChEMBL	CHEMBL1487540
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
54517	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
469652	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
54516	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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