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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	A 77636 hydrochloride
Molecular formula	C20H28ClNO3
IUPAC name	(1R,3S)-3-(1-adamantyl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol;hydrochloride
Molecular weight	365.898
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	None
Synonyms	A-255 CCG-221433 MolPort-039-052-174 Tox21_500129 A-77636 hydrochloride CHEMBL1256876 SCHEMBL1878106 [(1R,3S)-3-(adamantan-1-yl)-5,6-dihydroxy-3,4-dihydro-1H-isochromen-1-yl]methanaminium chloride (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride 3-(1'-Adamantyl)-1-aminomethyl-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyran hydrochloride AKOS025147304 LP00129 SR-01000075355-1 A-77636 (hydrochloride) CHEBI:64078 NCGC00093620-01 UNII-WA6RGP1J4W (1R,3S)-1-(aminomethyl)-3-(tricyclo[3.3.1.13,7]dec-1-yl)-3,4-dihydro-1H-isochromene-5,6-diol hydrochloride A77636 hydrochloride DTXSID1042576 SMR000326988 (1r-cis)-1-(aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-[1h]-2-benzopyran-5,6-diol hydrochloride B6837 MLS001056780 SR-01000075355-3 A-77636 HCl NCGC00260814-01 WA6RGP1J4W (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol hydrochloride AKOS024456753 EU-0100129 SR-01000075355 145307-34-2 [ Show all ]
Inchi Key	BWHPNJVKFAPVOG-QYFJGNGUSA-N
Inchi ID	InChI=1S/C20H27NO3.ClH/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20;/h1-2,11-13,17-18,22-23H,3-10,21H2;1H/t11?,12?,13?,17-,18-,20?;/m0./s1
PubChem CID	9951033
ChEMBL	CHEMBL1256876
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
34459	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
34458	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
467154	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
34460	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
34456	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
34457	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
467153	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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