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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000026289
Molecular formula	C25H31FN4O3S
IUPAC name	1-(cyclobutanecarbonyl)-N-[2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl]-2,3-dihydroindole-5-sulfonamide
Molecular weight	486.606
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.0
Synonyms	CCG-28599 ZINC61943425 HMS2323F17 AC1MMGZ0 MLS000876877 1-(cyclobutanecarbonyl)-N-[2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl]-2,3-dihydroindole-5-sulfonamide MCULE-1819663550 AKOS001799420 CHEMBL1508256 1-(cyclobutylcarbonyl)-N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}indoline-5-sulfonamide MLS000091742 [ Show all ]
Inchi Key	FQARDFZKKUJJKS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31FN4O3S/c26-22-6-1-2-7-24(22)29-16-14-28(15-17-29)13-11-27-34(32,33)21-8-9-23-20(18-21)10-12-30(23)25(31)19-4-3-5-19/h1-2,6-9,18-19,27H,3-5,10-17H2
PubChem CID	3238607
ChEMBL	CHEMBL1508256
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
84536	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
84534	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
84535	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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