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GPCR

Name5-hydroxytryptamine receptor 2A
SpeciesMus musculus (Mouse)
GeneHtr2a
Synonymserotonin 5HT-2 receptor
5Ht-2
'D' receptor
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
5-HT2A receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length471
Amino acid sequenceMEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYKSSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
UniProtP35363
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5377
IUPHARN/A
DrugBankN/A

Ligand

NameMLS001183932
Molecular formulaC17H18Cl2N4O4
IUPAC name2-[4-[(2,4-dichlorophenyl)methyl]piperazin-1-yl]pyrimidine;oxalic acid
Molecular weight413.255
Hydrogen bond acceptor8
Hydrogen bond donor2
XlogPNone
SynonymsCHEMBL1470751
SMR000502296
HMS2833O05
Inchi KeyGJIRPOWAHRVHDO-UHFFFAOYSA-N
Inchi IDInChI=1S/C15H16Cl2N4.C2H2O4/c16-13-3-2-12(14(17)10-13)11-20-6-8-21(9-7-20)15-18-4-1-5-19-15;3-1(4)2(5)6/h1-5,10H,6-9,11H2;(H,3,4)(H,5,6)
PubChem CID23724215
ChEMBLCHEMBL1470751
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessPartition coefficient log P of this ligand is not available.

Experimental Data

ParameterValueReferenceDatabase source
EC501290.0 nMPubChem BioAssay data setChEMBL

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