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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000059215
Molecular formula	C23H25N3O
IUPAC name	1-[(3-phenylmethoxyphenyl)methyl]-4-pyridin-2-ylpiperazine
Molecular weight	359.473
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.1
Synonyms	1-[(3-phenylmethoxyphenyl)methyl]-4-(2-pyridinyl)piperazine BDBM62764 MolPort-002-150-263 1-[3-(benzyloxy)benzyl]-4-(2-pyridinyl)piperazine cid_1378308 SMR000069679 AC1LQLSN 1-[(3-phenylmethoxyphenyl)methyl]-4-pyridin-2-yl-piperazine Oprea1_374709 1-[3-(benzyloxy)benzyl]-4-(pyridin-2-yl)piperazine HMS2433E21 STL328292 1-(3-benzoxybenzyl)-4-(2-pyridyl)piperazine AKOS022096006 MLS002539761 1-[(3-phenylmethoxyphenyl)methyl]-4-pyridin-2-ylpiperazine CHEMBL1379426 SCHEMBL12259121 AB00085429-01 MCULE-3960651724 ZINC1229294 [ Show all ]
Inchi Key	IKWKOVXTRGCSEM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25N3O/c1-2-7-20(8-3-1)19-27-22-10-6-9-21(17-22)18-25-13-15-26(16-14-25)23-11-4-5-12-24-23/h1-12,17H,13-16,18-19H2
PubChem CID	1378308
ChEMBL	CHEMBL1379426
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
135719	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
135718	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
135717	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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