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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-{4-[4-(Furan-2-carbonyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione
Molecular formula	C21H23N3O4
IUPAC name	2-[4-[4-(furan-2-carbonyl)piperazin-1-yl]butyl]isoindole-1,3-dione
Molecular weight	381.432
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.0
Synonyms	MLS001385330 ASN 07610692 ZINC4967375 HMS2492O24 AC1LDD1H REGID_for_CID_646155 2-[4-[4-(furan-2-carbonyl)piperazin-1-yl]butyl]isoindole-1,3-dione MLS000030130 AKOS000794843 SMR000008086 CHEMBL1324852 [ Show all ]
Inchi Key	IDNJGJKFUHTLFV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H23N3O4/c25-19-16-6-1-2-7-17(16)20(26)24(19)10-4-3-9-22-11-13-23(14-12-22)21(27)18-8-5-15-28-18/h1-2,5-8,15H,3-4,9-14H2
PubChem CID	646155
ChEMBL	CHEMBL1324852
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
130640	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
130639	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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