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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 2A
Species	Mus musculus (Mouse)
Gene	Htr2a
Synonym	serotonin 5HT-2 receptor 5Ht-2 'D' receptor 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 5-HT2A receptor 5-HT-2A 5-HT-2 Serotonin receptor 2A [ Show all ]
Disease	N/A for non-human GPCRs
Length	471
Amino acid sequence	MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYKSSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
UniProt	P35363
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5377
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	MLS000735483
Molecular formula	C22H28ClNO
IUPAC name	[4-[(4-chlorophenyl)methyl]-1-(3-phenylpropyl)piperidin-4-yl]methanol
Molecular weight	357.922
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.1
Synonyms	[4-(4-chlorobenzyl)-1-(3-phenylpropyl)-4-piperidinyl]methanol HMS2660A14 SMR000318269 [4-(4-chlorobenzyl)-1-(3-phenylpropyl)piperidin-4-yl]methanol MCULE-6030462392 ZINC13596042 CHEMBL1540643 [ Show all ]
Inchi Key	AEKKSGFBUSUPIU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28ClNO/c23-21-10-8-20(9-11-21)17-22(18-25)12-15-24(16-13-22)14-4-7-19-5-2-1-3-6-19/h1-3,5-6,8-11,25H,4,7,12-18H2
PubChem CID	16191719
ChEMBL	CHEMBL1540643
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	76076.0 nM	PubChem BioAssay data set	ChEMBL

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