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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N-(4-ethoxyphenyl)-3-[4-(2-fluorophenyl)piperazin-1-yl]propanamide
Molecular formula	C21H26FN3O2
IUPAC name	N-(4-ethoxyphenyl)-3-[4-(2-fluorophenyl)piperazin-1-yl]propanamide
Molecular weight	371.456
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.1
Synonyms	3-[4-(2-fluorophenyl)piperazino]-N-p-phenetyl-propionamide MCULE-9159247815 SR-01000595091-3 BDBM114618 N-(4-ethoxyphenyl)-3-[4-(2-fluorophenyl)-1-piperazinyl]propanamide cid_4226151 SR-01000595091 AC1N5XR7 MLS000521309 ZINC2939538 HMS2464F11 SR-01000595091-1 AKOS002132319 MolPort-007-953-084 CHEMBL1560475 SMR000131717 [ Show all ]
Inchi Key	BZQNGDFWFBIFAC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H26FN3O2/c1-2-27-18-9-7-17(8-10-18)23-21(26)11-12-24-13-15-25(16-14-24)20-6-4-3-5-19(20)22/h3-10H,2,11-16H2,1H3,(H,23,26)
PubChem CID	4226151
ChEMBL	CHEMBL1560475
IUPHAR	N/A
BindingDB	114618
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
36705	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
467444	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
36704	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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