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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-bromo-2-methoxy-6-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]phenol
Molecular formula	C16H19BrN4O2
IUPAC name	4-bromo-2-methoxy-6-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]phenol
Molecular weight	379.258
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.3
Synonyms	AC1LQHOW Oprea1_093432 CHEMBL1338732 SR-01000208636-1 4-bromo-2-methoxy-6-{[4-(2-pyrimidinyl)-1-piperazinyl]methyl}phenol MLS001001135 BDBM114628 SMR000496336 cid_1376210 SR-01000208636-3 4-bromo-2-methoxy-6-[[4-(2-pyrimidinyl)-1-piperazinyl]methyl]phenol AB00084780-01 MolPort-002-149-276 SR-01000208636 4-bromanyl-2-methoxy-6-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]phenol HMS2839H08 4-bromo-2-methoxy-6-[[4-(2-pyrimidyl)piperazino]methyl]phenol [ Show all ]
Inchi Key	BOYYZPFWQQQUAH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H19BrN4O2/c1-23-14-10-13(17)9-12(15(14)22)11-20-5-7-21(8-6-20)16-18-3-2-4-19-16/h2-4,9-10,22H,5-8,11H2,1H3
PubChem CID	1376210
ChEMBL	CHEMBL1338732
IUPHAR	N/A
BindingDB	114628
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29290	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
466525	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
29289	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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