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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SR-01000181557
Molecular formula	C22H35N3O4
IUPAC name	ethyl 4-[[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]methyl]piperazine-1-carboxylate
Molecular weight	405.539
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.0
Synonyms	4-[[4-[2-hydroxy-3-(1-piperidinyl)propoxy]phenyl]methyl]-1-piperazinecarboxylic acid ethyl ester ethyl 4-{4-[2-hydroxy-3-(1-piperidinyl)propoxy]benzyl}-1-piperazinecarboxylate SR-01000181557-3 CHEMBL1313562 MLS001008223 ethyl 4-[[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]methyl]piperazine-1-carboxylate BDBM114621 HMS2835M14 cid_23723421 MolPort-005-158-431 4-[4-(2-hydroxy-3-piperidino-propoxy)benzyl]piperazine-1-carboxylic acid ethyl ester ethyl 4-[[4-(2-oxidanyl-3-piperidin-1-yl-propoxy)phenyl]methyl]piperazine-1-carboxylate SR-01000181557-1 MCULE-9212712492 ethyl 4-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)benzyl]piperazine-1-carboxylate SMR000499474 [ Show all ]
Inchi Key	GHTYYFHWUZRTGZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H35N3O4/c1-2-28-22(27)25-14-12-24(13-15-25)16-19-6-8-21(9-7-19)29-18-20(26)17-23-10-4-3-5-11-23/h6-9,20,26H,2-5,10-18H2,1H3
PubChem CID	23723421
ChEMBL	CHEMBL1313562
IUPHAR	N/A
BindingDB	114621
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
96797	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
96796	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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