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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000033389
Molecular formula	C23H24N4O2
IUPAC name	N-(4-phenoxyphenyl)-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide
Molecular weight	388.471
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.6
Synonyms	697282-58-9 JS-2032 N-(4-phenoxyphenyl)-2-[4-(2-pyridinyl)-1-piperazinyl]acetamide BDBM45364 MLS000047378 N-(4-phenoxyphenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]acetamide cid_3237037 N-(4-phenoxyphenyl)-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide SR-01000607661-2 AC1MMDHK KS-00003M7O N-(4-phenoxyphenyl)-2-[4-(2-pyridinyl)piperazino]acetamide MolPort-002-078-291 HMS2301O14 N-(4-phenoxyphenyl)-2-(4-pyridin-2-ylpiperazin-1-yl)ethanamide ZINC4111685 AKOS002133075 MCULE-5660087991 N-(4-phenoxyphenyl)-2-[4-(2-pyridyl)piperazino]acetamide CHEMBL1527459 N-(4-PHENOXYPHENYL)-2-(4-(2-PYRIDINYL)-1-PIPERAZINYL)ACETAMIDE SR-01000607661 [ Show all ]
Inchi Key	IREYBTTUTCTPMN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H24N4O2/c28-23(18-26-14-16-27(17-15-26)22-8-4-5-13-24-22)25-19-9-11-21(12-10-19)29-20-6-2-1-3-7-20/h1-13H,14-18H2,(H,25,28)
PubChem CID	3237037
ChEMBL	CHEMBL1527459
IUPHAR	N/A
BindingDB	45364
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
139900	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
139898	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
139899	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
139901	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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