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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000082072
Molecular formula	C24H29N7O
IUPAC name	4-(3,4-dihydro-2H-quinolin-1-yl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazin-2-amine
Molecular weight	431.544
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.5
Synonyms	AC1LT38F MolPort-000-488-743 4-(3,4-dihydro-2H-quinolin-1-yl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazin-2-amine CHEMBL1576495 SR-01000298183-1 4-{[4-(3-methoxyphenyl)piperazinyl]methyl}-6-(1,2,3,4-tetrahydroquinolyl)-1,3, 5-triazine-2-ylamine MLS000052567 ZINC1419213 AKOS002204106 4-(3,4-dihydroquinolin-1(2H)-yl)-6-{[4-(3-methoxyphenyl)piperazin-1-yl]methyl}-1,3,5-triazin-2-amine HMS2298L09 ST50132732 726198-71-6 MLS002548480 4-(3,4-dihydro-1(2H)-quinolinyl)-6-{[4-(3-methoxyphenyl)-1-piperazinyl]methyl}-1,3,5-triazin-2-amine SR-01000298183 4-[3,4-dihydro-1(2H)-quinolinyl]-6-{[4-(3-methoxyphenyl)piperazino]methyl}-1,3,5-triazin-2-amine MCULE-5865533311 STK203246 [ Show all ]
Inchi Key	DRBZYDQLNLYGTC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29N7O/c1-32-20-9-4-8-19(16-20)30-14-12-29(13-15-30)17-22-26-23(25)28-24(27-22)31-11-5-7-18-6-2-3-10-21(18)31/h2-4,6,8-10,16H,5,7,11-15,17H2,1H3,(H2,25,26,27,28)
PubChem CID	1500638
ChEMBL	CHEMBL1576495
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
66823	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
66822	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
66821	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
66820	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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