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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001165031
Molecular formula	C20H21N3O2
IUPAC name	2-[4-(cyclopentylamino)quinazolin-2-yl]-6-methoxyphenol
Molecular weight	335.407
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.4
Synonyms	6-[4-(cyclopentylamino)-1H-quinazolin-2-ylidene]-2-methoxycyclohexa-2,4-dien-1-one cid_5922798 AC1OAJU5 (6E)-6-[4-(cyclopentylamino)-1H-quinazolin-2-ylidene]-2-methoxycyclohexa-2,4-dien-1-one STK552396 799799-44-3 HMS2873E22 (6E)-6-[4-(cyclopentylamino)-1H-quinazolin-2-ylidene]-2-methoxy-1-cyclohexa-2,4-dienone AKOS005479791 MolPort-002-588-278 2-[4-(cyclopentylamino)quinazolin-2-yl]-6-methoxyphenol CHEMBL1597289 ZINC96901699 AC1NZZVI MCULE-8474395152 (6E)-6-[4-(cyclopentylamino)-1H-quinazolin-2-ylidene]-2-methoxy-cyclohexa-2,4-dien-1-one BDBM58374 SMR000540224 [ Show all ]
Inchi Key	GJRFSBHLTQGPQZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H21N3O2/c1-25-17-12-6-10-15(18(17)24)20-22-16-11-5-4-9-14(16)19(23-20)21-13-7-2-3-8-13/h4-6,9-13,24H,2-3,7-8H2,1H3,(H,21,22,23)
PubChem CID	3787353
ChEMBL	CHEMBL1597289
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
560355	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
560353	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
560354	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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