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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3946540
Molecular formula	C21H25ClN2O2
IUPAC name	(2S)-2-[(3-chlorophenoxy)methyl]-4-[2-(2,3-dihydroindol-1-yl)ethyl]morpholine
Molecular weight	372.893
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.1
Synonyms	US9079895, 23s BDBM186935 QAJBOIGVHPCSNX-FQEVSTJZSA-N (S)-2-((3-chlorophenoxy)methyl)-4-(2-(indolin-1-yl)ethyl)morpholine SCHEMBL14060270
Inchi Key	QAJBOIGVHPCSNX-FQEVSTJZSA-N
Inchi ID	InChI=1S/C21H25ClN2O2/c22-18-5-3-6-19(14-18)26-16-20-15-23(12-13-25-20)10-11-24-9-8-17-4-1-2-7-21(17)24/h1-7,14,20H,8-13,15-16H2/t20-/m0/s1
PubChem CID	71061709
ChEMBL	CHEMBL3946540
IUPHAR	N/A
BindingDB	186935
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
543331	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
543342	5-hydroxytryptamine receptor 1D	Q61224	Htr1d	Mus musculus (Mouse)	374
543335	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
543338	5-hydroxytryptamine receptor 2B	Q02152	Htr2b	Mus musculus (Mouse)	479
543332	5-hydroxytryptamine receptor 2C	P34968	Htr2c	Mus musculus (Mouse)	459
543337	Alpha-1A adrenergic receptor	P97718	Adra1a	Mus musculus (Mouse)	466
543341	Alpha-1B adrenergic receptor	P97717	Adra1b	Mus musculus (Mouse)	514
543333	Alpha-1D adrenergic receptor	P97714	Adra1d	Mus musculus (Mouse)	562
543340	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
543334	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444
543339	D(3) dopamine receptor	P30728	Drd3	Mus musculus (Mouse)	446
543336	D(4) dopamine receptor	P51436	Drd4	Mus musculus (Mouse)	387

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