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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ABT-866
Molecular formula	C12H15N3O2S
IUPAC name	N-[3-(1H-imidazol-5-ylmethyl)phenyl]ethanesulfonamide
Molecular weight	265.331
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.4
Synonyms	Ethanesulfonamide, N-[3-(1H-imidazol-5-ylmethyl)phenyl]- A-286666 BDBM50118705 N-(3-(1H-imidazol-4-ylmethyl)phenyl)ethanesulfonamide Ethanesulfonamide, N-(3-(1H-imidazol-4-ylmethyl)phenyl)- SCHEMBL5612868 Ethanesulfonic acid [3-(1H-imidazol-4-ylmethyl)-phenyl]-amide ABT 866 N-[3-(1H-imidazol-4-ylmethyl)-phenyl]ethanesulfonamide 258526-74-8 Ethanesulfonamide, N-(3-(1H-imidazol-5-ylmethyl)phenyl)- UNII-P7JGJ12E1W A 286666 N-(3-((1H-imidazol-4-yl)methyl)phenyl)ethanesulfonamide CHEMBL326702 P7JGJ12E1W 371790-02-2 [ Show all ]
Inchi Key	ROUIPNDCVDWYEH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H15N3O2S/c1-2-18(16,17)15-11-5-3-4-10(6-11)7-12-8-13-9-14-12/h3-6,8-9,15H,2,7H2,1H3,(H,13,14)
PubChem CID	9838192
ChEMBL	CHEMBL326702
IUPHAR	N/A
BindingDB	50118705
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
301535	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
301537	Alpha-1A adrenergic receptor	O02824	ADRA1A	Oryctolagus cuniculus (Rabbit)	466
301538	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
301541	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
301542	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
301544	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
301540	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
301545	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
301536	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
301543	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
301539	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453

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