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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AGN-192172
Molecular formula	C12H17N5
IUPAC name	N-(4,5-dihydro-1H-imidazol-2-yl)-5-methyl-1,2,3,4-tetrahydroquinoxalin-6-amine
Molecular weight	231.303
Hydrogen bond acceptor	3
Hydrogen bond donor	4
XlogP	0.7
Synonyms	CHEMBL49284 BDBM50052881 D0L6JS Imidazolidin-2-ylidene-(5-methyl-1,2,3,4-tetrahydro-quinoxalin-6-yl)-amine
Inchi Key	PGOVKWAJCVAZNG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H17N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-3,13-14H,4-7H2,1H3,(H2,15,16,17)
PubChem CID	9816048
ChEMBL	CHEMBL49284
IUPHAR	N/A
BindingDB	50052881
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
259278	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
259276	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
259277	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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