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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL49137
Molecular formula	C12H13N5
IUPAC name	N-(4,5-dihydro-1H-imidazol-2-yl)-5-methylquinoxalin-6-amine
Molecular weight	227.271
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	0.3
Synonyms	91147-45-4 L005026 BDBM50052880 SCHEMBL15195137 DTXSID00238427 AC1L4G4B N-(4,5-dihydro-1H-imidazol-2-yl)-5-methylquinoxalin-6-amine SCHEMBL7028091 6-Quinoxalinamine, N-(4,5-dihydro-1H-imidazol-2-yl)-5-methyl- Imidazolidin-2-ylidene-(5-methyl-quinoxalin-6-yl)-amine AGN-191103 QZUXRMOPAGPTIY-UHFFFAOYSA-N 5-Methyl-6-(2-imidazolin-2-ylamino)quinoxaline [ Show all ]
Inchi Key	QZUXRMOPAGPTIY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H13N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-5H,6-7H2,1H3,(H2,15,16,17)
PubChem CID	185076
ChEMBL	CHEMBL49137
IUPHAR	N/A
BindingDB	50052880
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
290832	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
290833	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
290835	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
290834	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
290831	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
290836	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
290830	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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