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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	76537-53-6
Molecular formula	C10H13N5
IUPAC name	8-piperazin-1-ylimidazo[1,2-a]pyrazine
Molecular weight	203.249
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	0.5
Synonyms	Imidazo[1,2-a]pyrazine, 8-(1-piperazinyl)- 8-Pdpr BDBM50002151 SCHEMBL5496661 A839966 CTK5E3085 8-(1-piperazinyl)imidazo[1,2-a]pyrazine AC1Q4X6M FT-0756627 Imidazo[1,2-a]pyrazine,8-(1-piperazinyl)- 8-Piperazin-1-yl-imidazo[1,2-a]pyrazine ZINC5117657 AC1L2YVL D0E5CI 8-(piperazin-1-yl)imidazo[1,2-a]pyrazine AKOS024075563 Imidazo(1,2-a)pyrazine, 8-(1-piperazinyl)- L-639,019 1-{IMIDAZO[1,2-A]PYRAZIN-8-YL}PIPERAZINE 8-piperazin-1-ylimidazo[1,2-a]pyrazine CHEMBL331036 8-(1-Piperazinyl)imidazo(1,2-a)pyrazine AC1Q1I52 DTXSID50227346 [ Show all ]
Inchi Key	NSHLOJVJEGEMSF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C10H13N5/c1-5-14(6-2-11-1)9-10-13-4-8-15(10)7-3-12-9/h3-4,7-8,11H,1-2,5-6H2
PubChem CID	131268
ChEMBL	CHEMBL331036
IUPHAR	N/A
BindingDB	50002151
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
230783	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
230784	Alpha-2A adrenergic receptor	Q28838	ADRA2A	Bos taurus (Bovine)	452
230785	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
230782	Beta-2 adrenergic receptor	Q8K4Z4	Adrb2	Cavia porcellus (Guinea pig)	418

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